Ubiquitin (Ub) modification of proteins plays a prominent role in the regulation of multiple cell processes, including endoplasmic reticulum-associated degradation (ERAD). Until recently, ubiquitination of substrates was thought to occur only via isopeptide bonds, typically to lysine residues. Several recent studies suggest that Ub can also be coupled to nonlysine residues by ester/thiolester b...

INTRODUCTION: Since Iran is located in the semi-arid belt, it has faced such issues as drought, dust crisis, and intensified migration. The assessment of effects climate change includes identifying some key aspects uncertainties used to estimate its impacts, context Atmosphere-Ocean General Circulation Models (AOGCMs): regional-scale climatology, statistical or dynamic downscaling methods, para...

1 CSIRO Agriculture Flagship, Centre for Environment and Life Sciences, Perth, Western Australia, Australia, 2 CSIRO Agriculture Flagship, Black Mountain Laboratories, Canberra, Australian Capital Territory, Australia, 3 CSIRO Agriculture Flagship, Queensland Bioscience Precinct, Brisbane, Queensland, Australia, 4 University of Western Australia Institute of Agriculture, University of Western A...

BACKGROUND Primary stability after implant placement is essential for osseointegration. It is important to understand the bone/implant interface for analyzing the influence of implant design on primary stability. In this study rigid polyurethane foam is used as artificial bone to evaluate the bone-implant interface and to identify where the torque is being generated during placement. METHODS ...

In this paper we consider the extent of our knowledge of global beetle diversity. Depending on the estimates adopted, some 70–95% of all beetle species remain to be formally described, and at the current rate of progress it could be more than 200 years until the task is completed. One of the reasons for this is the difficulty of adequately sampling tropical beetle faunas and thereby ensuring su...

This paper described the archtecture of a hyperdocument system intended to provide access to a coherent body of knowledge, consisting of structured knowledge, text, graphics, data and executable models. The main focus of the research is in intermediate structure added to the documents to support the links between the structured knowledge and the textual knowledge. The system is implemented in a...

V. Haverd, M. R. Raupach, P. R. Briggs, J. G. Canadell, S. J. Davis, R. M. Law, C. P. Meyer, G. P. Peters, C. Pickett-Heaps, and B. Sherman CSIRO Marine and Atmospheric Research, P.O. Box 3023, Canberra ACT 2601, Australia University of California, Dept. of Earth System Science, Irvine, CA, USA CSIRO Marine and Atmospheric Research, PB1, Aspendale, Victoria 3195, Australia CICERO, P.O. Box 1129...

Senior Research Scientist and CSIRO Julius Fellow, CSIRO CCI Division, GPO Box 664, Canberra, ACT 2601 Director, Cloud Computing and Distributed Systems (CLOUDS) Lab, Department of Computing and Information Systems, The University of Melbourne, Australia University of Zurich, Department of Informatics, Binzmühlestrasse 14, CH-8050 Zurich, Switzerland Research Scientist, CSIRO CCI Division, GPO ...