background: many natural products from plants have been recognized to exert anticancer activity. in this study, ethanolic extracts of selected medicinal herbs from iranian flora including alyssum homolocarpum fisch. (from seeds), urtica dioica l. (from aerial parts), cichorium intybus l. (from roots) and solanum nigrum l. (from fruits), were evaluated for their cytotoxic effect on different cel...

considering multiple reports on cytotoxic activity of the artemisia genus and its phytochemicals, in the current study a. armeniaca lam. and the three components isolated from the plant were subjected to cytotoxic studies. analytical fractionation of a. armeniaca aerial parts for the first time was directed to the isolation of 7-hydroxy-8-(4-hydroxy-3-methylbutoxy) comarin (armenin), 8-hydroxy-...

      It has been reported that different species of Euphorbia (Euphorbiaceae) have antitumor activity. Some reports also show that these plants have potential cytotoxic effect against different cell lines. In a program to screen the cytotoxicity of Iranian native plants, Euphorbia macroclada Boiss. was collected, identified, and the cytotoxic activity of dichloromethane, ethy...

objective(s): regarding the presence of many active biological constituents in avicennia marina, the present investigation was carried out to study cytotoxic activity of crude methanol leave extract and column chromatographic fractions of a. marina against mda-mb 231 cell line (human breast cancer cell) and hek (human embryonic kidney cell) line .   materials and methods: the anticancer activit...

Considering multiple reports on cytotoxic activity of the Artemisia genus and its phytochemicals, in the current study A. armeniaca Lam. and the three components isolated from the plant were subjected to cytotoxic studies. Analytical fractionation of A. armeniaca aerial parts for the first time was directed to the isolation of 7-hydroxy-8-(4-hydroxy-3-methylbutoxy) comarin (armenin), 8-hydroxy-...

objective: homalium letestui pellegr (flacourtiaceae) is used in traditional medicine in parts of nigeria for the treatment of malaria, ulcer, and inflammatory diseases and as an aphrodisiac. this investigation was aimed to evaluate the cytotoxic, immunomodulatory, and antileishmanial properties of stem extract and fractions of homalium letestui (h. letestui). materials and methods: cytotoxic a...

Considering multiple reports on cytotoxic activity of the Artemisia genus and its phytochemicals, in the current study A. armeniaca Lam. and the three components isolated from the plant were subjected to cytotoxic studies. Analytical fractionation of A. armeniaca aerial parts for the first time was directed to the isolation of 7-hydroxy-8-(4-hydroxy-3-methylbutoxy) comarin (armenin), 8-hydroxy-...

The present study was designed to investigate the anti-melanogenic and cytotoxic activities of methanol extract of Phlomis kurdica. The antioxidant and anti-tyrosinase activity of MeOH extract from P. kurdica (MPk) were examined by DPPH radical scavenging and mushroom tyrosinase activity assays (in vitro), respectively. Furthermore, the effect of MPk on the melanin content, cellular tyrosinase ...

a series of fluoroquinolone derivatives holding triazolidindione moieties have been synthesized and proved to be cytotoxic agents in vitro particularly against cancer cell lines (sknmc, mcf7, a2780-cp, sw48, a549, kb, ht-29, hepg 2 ). the cytotoxic activity was assessed using mtt colorimetric assay. our compounds had less cytotoxicity than doxorubicin in all studied cell lines.