Cytotoxicity presents one of the required criteria in biological evaluation medical devices. In this study, semi-direct contact test was used to evaluate potential cytotoxicity hydrogel wound dressings compared conventional extract test. Three types sheets were fabricated from poly(vinyl alcohol) (PVA) by gamma irradiation: Bare sheets, silver (Ag)-coated and Aloe vera (AV)-coated sheets. test,...

Cytotoxicity of 14 glove materials representing 4 natural rubber latex, 6 synthetic rubber and 4 synthetic polymeric materials was evaluated using dimethylthiazol diphenyltetrazolium (MTT), agar overlay and filter diffusion tests. Cell responses after contact with extracts of glove materials and contact with glove materials were assessed. One synthetic rubber glove (nitrile rubber) and 2 synthe...

The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 ACP/TiO2/ /ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there no significant decrease the survival healthy cells exposed ...

background: angiogenesis, the formation of new blood vessels from preexisting ones, is one of the most important physiological and pathological processes occur in the body. in the pathological conditions such as tumor growth, psoriasis, corneal neovascularization and rheumatoid arthritis, angiogenesis is crucially required for the devolopment of the disease. zataria multiflora as a member of la...

Because of the need for more effective and less harmful antifungal therapies, and interest in the synthesis of new carboximidamides, the goal of this study was to determine the antifungal and anti-enzyme activities of some new pyrazole carboximidamides and their cytotoxicity. For this purpose, tests were performed to evaluate: minimum inhibitory concentration (MIC) and minimum fungicidal concen...

OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...

The selective effects of 24 agents on mouse spleen effector functions involved in the immune responses to sheep erythrocytes have been demonstrated. Five tests were used to assay the effector functions: the comple ment-dependent cellular cytotoxicity test, which mea sures complement-mediated lysis in the presence of anti body excreted from B-cell effectors; the complement-in dependent cellular ...