background: the sry gene (sry) provides instructions for making a transcription factor called the sex-determining region y protein. the sex-determining region y protein causes a fetus to develop as a male. in this study, sry of 15 spices included of human, chimpanzee, dog, pig, rat, cattle, buffalo, goat, sheep, horse, zebra, frog, urial, dolphin and killer whale were used for determine of bioi...

Lukáš Pravda, Karel Berka, Radka Svobodová Vařeková, David Sehnal, Pavel Banáš, Roman Laskowski, Jaroslav Koča*, Michal Otyepka* 1 National Centre for Biomolecular Research, Faculty of Science and CEITEC Central European Institute of Technology, Masaryk University Brno, Kamenice 5, 625 00 Brno-Bohunice, Czech Republic, 2 Regional Centre of Advanced Technologies and Materials, Department of Phys...

The other 90% of the protein: Assessment beyond the Cas for CASP8 template-based and high-accuracy models Daniel A. Keedy, Christopher J. Williams, Jeffrey J. Headd, W. Bryan Arendall III, Vincent B. Chen, Gary J. Kapral, Robert A. Gillespie, Jeremy N. Block, Adam Zemla, David C. Richardson, and Jane S. Richardson* 1Department of Biochemistry, Duke University Medical Center, Durham, North Carol...

Introduction: Stomach cancer is the fourth most common and second leading cause of death in world. In addition to significant costs, it imposes many problems on families that a proper justification for identifying related biomarkers. Method : The miRBASE website was used find bioinformatics information. addition, mirWALK miRNASN databases were searched miRNAs To pathways, DAVID KEGG adopted. Re...

different treatment strategies of alzheimer's disease (ad) are being studied for treating or slowing the progression of ad. many pharmaceutically important regulation systems operate through proteins as drug targets. here, we investigate the drug target proteins in beta-amyloid (aβ) injected rat hippocampus treated with lavandula angustifolia (la) by proteomics techniques. the reported stu...

1524 October 2008 | Volume 5 | Issue 10 | e209 Correction: Bioinformatics and Multiepitope DNA Immunization to Design Rational Snake Antivenom Simon C. Wagstaff, Gavin D. Laing, R. David G. Theakston, Christina Papaspyridis, Robert A. Harrison Correction for: Wagstaff SC, Laing GD, Theakston RDG, Papaspyridis C, Harrison RA (2006) Bioinformatics and multiepitope DNA immunization to design ratio...

OBJECTIVE Keloid disease (KD) is a benign fibroproliferative skin tumor that results from abnormal wound healing and has no single definitive treatment. This study aims to identify KD biomarkers, which are cellular mediators that can serve as indicators of normal, pathological, and therapeutic processes. METHODS Bioinformatics analytic approaches, including comprehensive literature searches a...

Background. Epicardial adipose tissue (EAT) is identified as an atypical fat depot surrounding the heart with a putative role in the involvement of metabolic disorders, including obesity, type-2 diabetes mellitus, and atherosclerosis. We profiled miRNAs in EAT of metabolic patients with coronary artery disease (CAD) and type-2 diabetes mellitus (T2DM) versus metabolically healthy patients by mi...