The human amniotic membrane known as the innermost single epithelial-covered layer provides many applications such as applicable anti-inflammatory and anti-cancer effects. These immunomodulatory effects belongs to the epithelial cells, a type of epiblast-derived fetal stem cells which currently used for regenerative medicine and transplantation. These cells are collected by author-prepared faci...

Epithelial tumors are rarely seen during the first two decades of life. We report a 17 year old male with primary transitional cell carcinoma (TCC) of the bladder.

The importance of extra cellular matrix (ECM) in development and function of different cells has been reported but little is known about its role in human endometrial epithelial cells. The aim of the present study was to examine effects of artificial ECM (Matrigel) and progesterone on the function and morphology of human endometrial epithelial cells in vitro. Methods: Endometrial samples were ...

Background and Objective: Mesenchymal stem cells (MSCs) promote metastasis in colorectal cancer; however, the mechanism underlying this process is not fully understood. Epithelial to mesenchymal transition (EMT) is a key step in tumor acquisition of metastatic phenotype. We aimed to investigate the effect of MSCs on the expression of EMT markers, as well as cancer stem cell markers in HT-29 col...

stem cell therapy has been applied for the treatment of degenerative diseases encompassing corneal disorders.this consideration is regarding the unique characteristics of stem cells including self-renewal and pluripotency. some corneal diseases result from deficiencies in the limbal region. in these conditions, limbal stem cell therapy is considered in which limbal stem cells are cultured in vi...

two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic human alveolar basal epithel...

introduction: this study was initiated to examine the effect of the ampullary and the isthmic primary cell cultures of human oviduct during long-term co-culture on two-cell mouse embryos. materials and methods: using a mechanical procedure, epithelial cells from ampullary (a) and isthmic (i) regions of the human oviduct were isolated and cultured in ham's f-10 with 10% fetal calf serum (fsc). t...

the importance of extra cellular matrix (ecm) in development and function of different cells has been reported but little is known about its role in human endometrial epithelial cells. the aim of the present study was to examine effects of artificial ecm (matrigel) and progesterone on the function and morphology of human endometrial epithelial cells in vitro. methods: endometrial samples were r...