I. Prolonged intermittent exposure to reduced environmental temperature (+ 2") produced in rats given a nutritionally well-balanced diet a decrease in the concentration of esterified fatty acids in the blood serum, liver and epididymal fat tissue. In the last there was a significant increase in the unesterified: esterified fatty acid ratio. The hepatic synthesis of fatty acids from [1-14C]aceta...

FoUR major classes of lipid are found in human serum: cholesterol and its esters, triglyceride, phospholipids and non-esterified fatty acids. They exist in aqueous solution because they are combined with protein to form lipoprotein complexes. The non-esterified fatty acids are bound to albumin, and the other lipids are associated with certain serum globulins. The nomenclature of the lipoprotein...

Three major regulatory steps can be recognized in the control of ketogenesis (Fig. 1): (1) regulation of the supply of the major ketogenic substrate, plasma non-esterified fatty acids, by control of their release from adipose tissue; (2) regulation in the liver of the relative fluxes of non-esterified fatty acids through the pathways of /3-oxidation and esterification; (3) regulation in the liv...

...................... • ...................... . Acknowledgements .....••••.•.•...••.....•..•.•.•...•..•. 2 Introduction ........................................... 3 Materials and Methods .......•....•.....••.•...••.•.••.. 7 Results ....••......•.•.....•..•.........••••.. o••••••••14 Di scl1ss ion .•...•....•••••...•....•....••••.•.......•... 17 Summary • ••••.•.••••••••.••.•..•.••.....•.•.•....

In the suckling newborn rat, blood ketone bodies begin to increase slowly 4h after birth and then rise sharply between 12 and 16h, whereas the major increase in plasma non-esterified fatty acids and liver carnitine occurs during the first 2h of life, parallel with the onset of suckling. In the starved newborn rat, which shows no increase in liver carnitine unless it is fed with a carnitine solu...

Functionally hepatectomized rabbits showed convulsions and coma within 2 hours after the intravenous injection of fat emulsion and heparin. Intravenous injection of the detergent triton prevented this syndrome, if given before the fat emulsion and heparin, and reversed it if given subsequently. Extremely high plasma non-esterified fatty acid levels were noted in rabbits showing the convulsive s...

Esterified astaxanthins are used as functional nutraceuticals and pigments in many food products. Unfortunately, the utilization is currently limited due to their chemical instability and poor water-solubility. In this study, esterified astaxanthins were quantified and purified from Haematococcus pluvialis using a novel and precise approach. By HPLC-(+)APCI-MS/MS, twenty esterified astaxanthin ...

A new procedure for the preparation of methyl esters from free fatty acids under mild conditions was investigated. Free fatty acids are dissolved in a mixture of chloroform-methanolic HCl-cupric acetate and kept at room temperature for 30 min for complete esterification. The method is suitable for esterification of long-chain acids, such as 18:0, and for very long chain acids, such as 24:0. Fat...

Impaired fatty acid metabolism has been implied in a number of diseased states such as multiple sclerosis, sudden cardiac death, insulin resistance, atherosclerosis and hypertension (Blaak, 2003; Oram & Bornfeldt, 2004; Pilz et al., 2007; Sarafidis & Bakris, 2007; Hon et al., 2009a, 2009b). The fatty acid status may be assessed in plasma, platelets, red blood cells, white blood cells and brain ...