Abstract Evaluation and power of seroprevalence studies depend on the performed serological assays. The aim this study was to assess four commercial tests from EUROIMMUN, DiaSorin, Abbott, Roche as well an in-house immunofluorescence neutralization test for their capability identify SARS-CoV-2 seropositive individuals in a high-prevalence setting. Therefore, 42 social working contacts German su...

Circulating antinuclear antibodies (ANA) are commonly present in the systemic autoimmune disease Systemic Lupus Erythematosus (SLE) and in other systemic rheumatic diseases, in humans as well as in dogs. The indirect immunofluorescence (IIF)-ANA test is the standard method for detecting ANA. Further testing for specific ANA with immunoblot techniques or ELISAs is routinely performed in humans t...

BACKGROUND Chronic hepatitis C virus (HCV) is associated with extra hepatic autoimmune disorders, while peg-IFNa-2a/RBV combination therapy may exacerbate these conditions. Autoantibodies to cytoplasmic structures, called rod and ring particles (RR), have strong associations with these patients and are identified by HEp-2 cells. OBJECTIVES Our purpose was to study the correlation of autoantib...

Recently, anti-deamidated gliadin antibodies were proposed for the serological diagnosis of celiac disease. We evaluate the specificity of different anti-deamidated gliadin antibodies ELISA in comparison with conventional anti-native gliadin kits. Serum samples from 46 non celiac patients were analyzed by five different quantitative ELISA for anti-native gliadin, anti-deamidated gliadin and ant...

Abstract We describe results of testing blood donors in London, UK, for severe acute respiratory disease coronavirus 2 (SARS-CoV-2) IgG before and after lockdown measures. Anonymized samples from 17–69 years age were tested using 3 assays: Euroimmun IgG, Abbott an immunoglobulin receptor-binding domain assay developed by Public Health England. Seroprevalence increased 3.0% prelockdown (week 13,...

BACKGROUND/AIM The purpose of this study was to determine the most frequent food and inhalant allergens leading to allergic sensitization in children in Van Province of Turkey. MATERIALS AND METHODS The study included 1052 serum samples with no diagnosis of allergy. The sera were tested with the Euroline Pediatric IgE test kit (EUROIMMUN, Germany). By using the EUROLineScan digital evaluation...