نتایج جستجو برای: familial support
تعداد نتایج: 710137 فیلتر نتایج به سال:
Evidence from cytogenetics, multipoint linkage analyses of familial melanoma, and loss of heterozygosity studies of familial and sporadic melanomas support localization of a melanoma susceptibfflty or tumor suppressor gene at chromosomal region 9p21—23. Recently, the inhibitor of cydlin-dependent kinase 4 (CDK4I; also known as p16@'4, multiple tumor suppressor 1, or CDKN2 gene) has been mappe...
This study examined the differential effects of familial configuration and support system failures in a sample of 256 college students. Regarding familial configuration, the results indicated that individuals who had experienced parental divorce were significantly more likely to have encountered parental hostility and/or lack of care, inadequate supervision when not in school, lack of concern b...
There are few studies of environmental factors in familial forms of schizophrenia. We investigated whether childhood adversity or environmental factors were associated with schizophrenia in a familial sample where schizophrenia is associated with the NOSA1P gene. We found that a cumulative adversity index including childhood illness, family instability and cannabis use was significantly associa...
Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia.
Plasma lipoprotein concentration, composition, and size were evaluated in two common familial forms of hypertriglyceridemia and compared with those in normal subjects. The very low density lipoproteins (VLDL) were triglyceride-enriched in familial hypertriglyceridemia (triglyceride/apoprotein B ratio: 25.7 +/- 8.9) as compared to normal (9.6 +/- 12.2, P < 0.001) or familial combined hyperlipide...
purpose: to report a relatively rare case of familial exudative vitreoretinopathy (fevr). patient and findings: a 13-year-old boy referred with decreased visual acuity of both eyes, specially right eye from 6 years ago. he had several ophthalmologist and optometrist visits and spectacle prescription without any improvement of vision. best corrected visual acuity (bcva) was 25 cm of count finger...
UNLABELLED Pancreatic cancer is projected to become the second leading cause of cancer-related death in the United States by 2020. A familial aggregation of pancreatic cancer has been established, but the cause of this aggregation in most families is unknown. To determine the genetic basis of susceptibility in these families, we sequenced the germline genomes of 638 patients with familial pancr...
The misfolding of the protein α-synuclein is a major contributor to Parkinson’s disease (PD). Three mutations (A53T, A30P and E46K) cause familial PD, and three newly discovered spliced variant forms of the protein (syn-126, syn-112, and syn-98) are also found in many PD patients. Little is known about whether these familial mutants can influence each other’s contributing properties and whether...
Creutzfeldt-Jakob disease (CJD), the first transmissible spongiform encephalopathy (TSE) to be described in humans, occurs in a sporadic, familial, or iatrogenic form. Other TSEs in humans, shown to be associated with specific prion protein gene mutations, have been reported in different parts of the world. These TSEs compose a heterogeneous group of familial diseases that traditionally have be...
Objective: Dependence and drug abuse are among the most important problems of the present age that have found global expansion. The consequences of these problems including mental, psychological, familial, cultural, economic, and social disorders have prevailed all social and cultural boundaries and threaten human health. Due to the effectiveness of social factors in the process of addiction wi...
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