BACKGROUND Cardiac stem cells (CSCs) play a vital role in cardiac homeostasis. A decrease in the efficiency of cardiac stem cells is speculated in various cardiac abnormalities. The maintenance of a healthy stem cell population is essential for the prevention of adverse cardiac remodeling leading to cardiac failure. Famotidine, a histamine-2 receptor antagonist, is currently used to treat ulcer...

The effect of histamine H2-receptor antagonist (famotidine) on the phosphorus-binding abilities of calcium carbonate and calcium lactate were examined in 13 chronic hemodialysis patients. In seven patients receiving calcium carbonate, famotidine (20 mg/d) was given because of gastroduodenal disorders, and calcium carbonate was replaced with calcium lactate as a phosphorus binder after 4 wk of t...

Background: Radioprotective effect of famotidine was previously shown on radiation induced micronuclei and chromosomal aberrations in human peripheral lymphocytes and mouse bone marrow cells however, its radioprotective property has never been studied in mouse spermatogenesis. It was also shown that vitamin C as an antioxidant also exert its radioprotective effect on many biological s...

background: about 40%-60% of schizophrenic patients are resistant to ordinary treatment, which result from interference with different neurotransmitter systems in the process of disease. the aim of present study was to determine the effect of famotidine on several symptoms of schizophrenia which was nonresponsive to neuroleptic treatment.   methods: 30 schizophrenic patients previously nonrespo...

Objective: Famotidine is an H2 receptor antagonist (H2RA) and has been shown to have antiviral properties in in-vitro studies. Pantoprazole one of the proton pump inhibitors (PPI). In this study, it was aimed compare efficacy with treatment COVID-19.
 Material-method: Patients who were hospitalized given famotidine pantoprazole for at least 48 hours included study. Demographic, clinical la...

The effect of resveratrol on the damage induced by methotrexate (MTX) in rat duodenum and jejunum tissue was investigated and evaluated in comparison with famotidine. The rats were divided into four groups as healthy group (HG), resveratrol+MTX (RMTX) group, famotidine+MTX (FMTX) group and the control group which received MTX (MTXC). RMTX group was given resveratrol 25 mg/kg and FMTX group famo...

Histamine H2 receptor antagonist are used in the clinical treatment of peptic ulcer. In vitro metaphase analysis and micronucleus assay were used to test the effect of Famotidine & Ranitidine on 60 Cobalt gamma-ray induced clastogenic effects. Heparinised whole blood was obtained from 6 healthy volunteers and was gamma irradiated with 3Gy. Lymphocyte cultures were initiated and aqueous solution...

A rapid, specific and sensitive high-performance liquid chromatographic method for the determination of famotidine in human plasma has been developed. Famotidine and the internal standard were chromatographically separated from plasma components using a Lichrocart Lichrospher 60 RP selec B cartridge for solid-phase separation with a mobile phase composed of 0.1 % (v/v) triethylamine in water (p...

A simple, selective and accurate reversed-phase high pressure liquid chromatogaphic method with UV detection at 274 nm has been developed for the determination of famotidine in human plasma. The procedure employed ranitidine as an internal standard (IS). A good chromatographic separation between famotidine, internal standard and interfering endogenous peaks was achieved using a a C18 column and...

Jul 1, 2011 . The oral acid suppressors famotidine and omeprazole have been widely used. To facilitate dosing, the omeprazole paste was combined with . with H2RAs, such as ranitidine or famotidine, 30–60 minutes prior to a meal would be a standard dose omeprazole, pantoprazole, or lansoprazole in more. Feb 25, 2015 .