Introduction This study presents the first direct investigation of fetal brain activity in utero using fMRI. Human fetal brain activity is usually studied indirectly by monitoring the changes in fetal heart rate and associated fetal movements, although recently fetal MEG has been attempted’. fMRI offers a safe and relatively robust method of monitoring fetal brain activity. This has major impli...

background: the aim of this study was to apply the nested-pcr and bioassay methods in detection and genotyping of toxoplasma gondii infection in provided sheep aborted fetus samples from qazvin province of iran. methods : eighteen sheep aborted fetal samples were studied by nested-pcr-rflp, histopathologi­cal observation and microbiological assay. bioassay in mice was carried out by inoculating...

BACKGROUND Although catechins are known to be powerful antioxidants, no reports have shown their transport to fetal organs. We investigated the distribution of catechins in fetal rat organs after maternal exposure to green tea extract (GTE). METHODS GTE (550 mg/kg) or water was fed orally to pregnant dams at 15.5 days of gestation, the dams were sacrificed and fetal organs were dissected 0, 0...

Fetal type posterior cerebral artery (FTPCA) is a variant of circulation brain, in which the distal part (PCA) perfused by branch internal carotid (ICA) via fetal communicating (fetal PCOM). In presence PCOM, paradoxical concurrent infarction anterior and may happen. We report 67-year-old man who presented with sudden onset right sided weakness aphasia, National Institutes Health Stroke Scale (...

Due to the low percentage of fetal DNA present in maternal plasma (< 10%) during early gestation, efficient extraction processes are required for successful downstream detection applications in non-invasive prenatal diagnostic testing. In this study, two extraction methods using similar chemistries but different workflows were compared for isolation efficiency and percent fetal DNA recovery. Th...

Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral organoids and human fetal brain, using genome-wide, base resolution DNA methylome and transcripto...