A carbapenem-resistant Serratia marcescens strain, 10mdr148, was identified in a Japanese hospital in 2010. The carbapenem resistance of this strain was attributed to the production of a novel metallo-β-lactamase (MBL), named SMB-1 (Serratia metallo-β-lactamase). SMB-1 possessed a zinc binding motif, H(Q)XHXDH (residues 116 to 121), H196, and H263 and was categorized as a member of subclass B3 ...

Swarna makshika (chalcopyrite) bhasma (SMB) has been used for different therapeutic purposes since long in Ayurveda. The present study is conducted to evaluate the effect of conventionally prepared SMB on different bio-chemical parameters in experimental animals, for providing scientific data base for its logical use in clinical practice. The genuine SMB was prepared by following classical tech...

Mass loss from the Greenland ice sheet over the past decade has caused the impression that the ice sheet has been behaving anomalously to the warming of the 1990s. We have reconstructed the recent (1866–2005) surface mass-balance (SMB) history of the Greenland ice sheet on a 5 5 km grid using a runoff-retention model based on the positive degree-day method. The model is forced with new datasets...

[1] The East Antarctic Ice Sheet is the largest, highest, coldest, driest, and windiest ice sheet on Earth. Understanding of the surface mass balance (SMB) of Antarctica is necessary to determine the present state of the ice sheet, to make predictions of its potential contribution to sea level rise, and to determine its past history for paleoclimatic reconstructions. However, SMB values are poo...

The role of SMA and SMB smooth muscle myosin heavy chain (MHC) isoforms in tonic and phasic contractions was studied in phasic (longitudinal ileum and stomach circular antrum) and tonic (stomach circular fundus) smooth muscle tissues of SMB knockout mice. Knocking out the SMB MHC gene eliminated SMB MHC protein expression and resulted in upregulation of the SMA MHC protein without altering the ...

A new type of electron ionization LC-MS with supersonic molecular beams (EI-LC-MS with SMB) is described. This system and its operational methods are based on pneumatic spray formation of the LC liquid flow in a heated spray vaporization chamber, full sample thermal vaporization and subsequent electron ionization of vibrationally cold molecules in supersonic molecular beams. The vaporized sampl...

A new improvement based on outlet fractionation and feedback has been developed for simulated moving bed (SMB) chromatography. In this contribution, this fractionation and feedback SMB (FF-SMB) concept is extended to the general scenario which integrates a simultaneous fractionation of both outlet streams. A model-based optimization approach, previously adopted to investigate single fractionati...

Simulated moving bed (SMB) chromatography is a highly efficient adsorption-based separation technology with various industrial applications. At present, its application has been successfully extended to the biochemical and pharmaceutical sectors. SMB possesses advantages of high product purity yield, large feed treatment capacity, simple process control due continuous operation mode mechanism, ...

Schema matching is recognized to be one of the basic operations required by the process of data and schema integration, and thus has a great impact on its outcome. We propose a new approach to combining matchers into ensembles, called Schema Matcher Boosting (SMB). This approach is based on a well-known machine learning technique, called boosting. We present a boosting algorithm for schema matc...