UNLABELLED This article discusses the possible cariostatic mechanisms of the action of fluoride. In the past, fluoride inhibition of caries was ascribed to reduced solubility of enamel due to incorporation of fluoride (F-) into the enamel minerals. The present evidence from clinical and laboratory studies suggests that the caries-preventive mode of action of fluoride is mainly topical. There is...

The present study revealed that the total fluoride level in human whole blood is closely related to the renal function. For the undialyzed patients who had not undergone hemodialysis, the total fluoride level in whole blood linearly increased with the increase of creatinine (Cr) value. The increased fluoride was found to be nonionic in the other blood part than serum, while the nonionic fluorid...

Incubation (30 degrees) of fat cell particulate fractions with fluoride before assay in the effective absence of fluoride results in activation of adenylate cyclase. Whereas the effect of fluoride (1.3 to 7 mM) when added to the assay was maximal in less than 2 min, 10 or 15 min of incubation before assay was usually required to produce maximal activation with any given concentration of fluorid...

The paper discusses a possible new concept of the role of fluoride and its mechanism of action in caries prevention. In the past fluoride inhibition of caries was ascribed to reduced solubility due to incorporation of fluoride (F) into the enamel minerals (firmly bound fluoride or fluorapatite). Based on the new findings, it appears that fluoride, either released into or present in the fluid ph...

objectives: fluoride therapy is important for control and prevention of dental caries. laser irradiation can increase fluoride uptake especially when combined with topical fluoride application. the objective of this study was to compare the effects of co 2 and diode lasers on enamel fluoride uptake in primary teeth. materials and methods: forty human primary molars were randomly assigned to fou...

OBJECTIVE To determine fluoride excretion under various conditions of fluoride intake and to estimate the fractional urinary excretion of fluoride in individual children participating in a school milk fluoridation scheme. DESIGN In the first part of the study, individual urine samples were collected from each of eight 4 to 5-year-old children for a continuous period of 55 h. For each child (n...

The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding ...

Background; Fluoride is an essential nutrient for the human body. The major routes of fluoride intake include food and drinking water, though the absorption of fluoride from food is much easier. The aim of this study was to evaluate the amount of fluoride in the soil and tomato and onion crops on farms of Zanjan. Methods; Three farms of each crop (tomato and onion) were selected randomly. Ea...

Introduction Fluoride (F−) is an important anion, present in various environmental, clinical and food samples. Small amounts of fluoride are vital for the human organism, but it is toxic in larger amounts. For adults the lethal dose is 0.20–0.35 g F− per kg body weight. Fluoride is widely used in various branches of industry and some fluoride compounds are formed as by-products in certain proce...