OBJECTIVE To examine the indications, risks, and surgical outcomes after tracheal reconstruction using cadaveric homograft in children. DESIGN Retrospective medical record review. SETTING Tertiary referral center. PATIENTS Ten children (4 boys and 6 girls). INTERVENTION Tracheal reconstruction using cadaveric homograft. MAIN OUTCOME MEASURES Cause of stenosis, number and type of proce...

OBJECTIVE Review of surgical repair of aortic root aneurysms using composite graft or homograft in children. METHODS A consecutive series of 34 children (mean age 10.8+/-5.4 years) who underwent elective aortic root replacement using composite graft or homograft from 1987 to 2003 (mean follow-up 5.7+/-3.7 years). RESULTS Preoperatively, the aortic annulus and aortic root average z-scores we...

Recent studies have shown that the red marrow is the principal antigenic component of a fresh homograft of iliac bone and that iliac bone tissue washed free from marrow is not demonstrably antigenic (Burwell and Gowland 1962, Burwell 1963). These findings clearly emphasise the necessity, when investigating the antigenicity of fresh cortical and cancellous bone, of cleansing the homograft of red...

BACKGROUND The pulmonary homograft has been used as an option in the correction of congenital cardiopathy with obstruction of the right ventricle exit tract. The long term results, however, are little satisfactory. OBJECTIVE Identify the risk factors associated to the dysfunction and the pulmonary homograft failure. METHODS Study with children submitted to the enlargement of the exit tract ...

Repeat aortic valve replacement (AVR) after freestanding homograft root replacement with reimplantation of the coronary arteries is challenging and risky, especially in patients with major homograft wall calcifications. Although new transcatheter techniques for AVR may offer an alternative in structurally degenerated homografts, they are not suitable to treat endocarditis. Here, the case is rep...

The aortic homograft has become the replacement valve of choice in the treatment of complicated endocarditis involving native and prosthetic aortic valves. Complications are rare, typically involving chronic leaflet degeneration causing valvular insufficiency or rarely chronic calcific stenosis. We present a case in which functional stenosis of the homograft valve was caused by compression and ...

Experience has shown that some frame-mounted homograft aortic valves, although competent immediately after mounting, are incompetent when subsequently presented for surgical use. Retraction and shrinkage of the cusps appears to be the cause of this change. Clinical and experimental studies have shown that shrinkage of homograft aortic valves occurs over an approximately five-day period after de...

OBJECTIVES The Ross procedure is the aortic valve-replacement procedure of choice in children. Nonetheless, late autograft re-operation for dilatation and/or valve regurgitation is of concern. We examined whether preoperative haemodynamic manifestation (e.g., stenosis, regurgitation and mixed aortic valve disease) affected late re-operation risk. METHODS Medical records of 227 children who un...