Abstract Introduction: There are many studies about the inhibitory effect of the esophageal distention (ED) on gastric motility. Recently, it has been shown that ED decreases the gastric secretions. It is well established that the inhibitory effect of ED is mediated by activation of vago-vagal inhibitory reflex. However, there is not any investigation about the effect of the reflex on the gast...

Gastric carcinosarcoma is a rare cancer of adults with poor prognosis compared with other gastric malignancies. To the best of our knowledge, the present report is the first case of gastric carcinosarcoma with chondroblastic differentiation in Iran. A 63-year-old man with epigastric pain was admitted to the surgery department. Abdominopelvic CT-scan showed a hypodense mass lesion in distal gast...

Background: Chronic inflammation and dys-regulation of the immune system mechanisms are now well established as primary triggers of gastric cancer and peptic ulcer disease. Galectin-9 (Gal-9) is a member of the galectin family and known as an inducer of cell aggregation, adhesion and apoptosis. Gal-9 interaction with its main ligand T-cell immunoglobulin and mucin domain protein-3 (Tim-3) leads...

Background:Upper gastrointestinal (GI) bleeding remains a problem in critically ill-newborns. The use of H2 blockers, by maintaining gastric pH ³ 4, reduces the risk of stress-ulceration and gastric hemorrhage. This study therefore, has evaluated the effects of short-term prophylactic‎ ranitidine in controlling gastric pH and prevention of GI bleeding in neonates. Methods: This randomized contr...

objective(s):mirnas have been proposed to be key regulators of tumorigenesis, progression and metastasis. however, their effect and prognostic value in gastric cancer is still poorly known. materials and methods: gastric cancer cell lines were cultured. tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time pcr (qrt-pcr) analysis. the tissue microarrays (tm...

abstract       background and objective: baba2 and hpa genes are involved in adherence of helicobacter pylori (h.pylori) to gastric mucosal tissue. this study aimed to investigate the frequency of these genes in isolates of h. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer.       methods: gastric biopsy samples were obtained from patients wit...

abstract injection of sulpiride (d2 receptor antagonist, antipsychotic drug) into vmn hypothalamus, increased gastric volume secretion and decreased gastric ph. the present study the effect of sch23390 (d1 dopamine receptor antagonist) on the gastric acid secretion and its acidity were studied. 70 rats were divided into 7 groups: two control groups, two sham groups given medicine solvents, a sc...

background: to asses the status of two representative genes of cag pai i.e caga and cage of helicobacter pylori strains infecting iranian patients suffered from various clinical outcomes using one-step pcr. methods: a total of 120 h. pylori infected patients including non-ulcer dyspepsia, nud (n=81), peptic ulcer disease, pud (n=17), and gastric carcinoma, gc (n= 22) referred for endoscopy or g...