نتایج جستجو برای: gastric epithelial cells
تعداد نتایج: 1520855 فیلتر نتایج به سال:
Bone morphogenetic protein (BMP) signaling within the gastrointestinal tract is complex. BMP ligands and their receptors are expressed in both epithelial and mesenchymal compartments, suggesting bidirectional signaling between these two entities. Despite an increasing interest in BMP signaling in gut physiology and pathologies, the distinct contribution of BMP signaling in the epithelium vs. th...
Rutten, Michael J., Kathy D. Bacon, Katie L. Marlink, Mark Stoney, Camie L. Meichsner, Fred P. Lee, Susan A. Hobson, Karin D. Rodland, Brett C. Sheppard, Donald D. Trunkey, Karen E. Deveney, and Clifford W. Deveney. Identification of a functional Ca21-sensing receptor in normal human gastric mucous epithelial cells. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G662–G670, 1999.—The pur...
Identification of a functional Ca21-sensing receptor in normal human gastric mucous epithelial cells
Rutten, Michael J., Kathy D. Bacon, Katie L. Marlink, Mark Stoney, Camie L. Meichsner, Fred P. Lee, Susan A. Hobson, Karin D. Rodland, Brett C. Sheppard, Donald D. Trunkey, Karen E. Deveney, and Clifford W. Deveney. Identification of a functional Ca21-sensing receptor in normal human gastric mucous epithelial cells. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G662–G670, 1999.—The pur...
Infection of Helicobacter pylori (H. pylori) changed the proliferation of gastric epithelial cells and decreased the expression of heat shock protein 70 (HSP70). However, the effects of H. pylori on the proliferation of gastric epithelial cells and the roles of HSP70 during the progress need further investigation. Objective. To investigate the effects of Helicobacter pylori (H. pylori) and heat...
Helicobacter pylori infection is associated with chronic gastritis, peptic ulceration, and gastric carcinoma. The potential role of CD95-mediated apoptosis was investigated in a panel of gastric biopsies obtained from patients with H. pylori-associated chronic gastritis (n = 29) and with noninfected normal mucosa (n = 10). Immunohistochemistry revealed increased CD95 receptor expression in epit...
Gastric mucosal inflammation can develop after challenge with noxious stimuli such as alcohol. Specially, alcohol stimulates the release of inflammatory cytokines but does not increase gastric acid secretion, leading to gastric mucosal damage. The plant sterol guggulsterone and its novel derivative GG-52 have been reported to inhibit nuclear factor-κB (NF-κB) signaling in intestinal epithelial ...
Background: Helicobacter pylori has been classified as the class I carcinogenic agent by world health organization. Colonization of the human stomach with H. pylori is a risk factor for gastroduodenal diseases. The secreted vacA toxin is an important H. pylori virulence factor that causes multiple alterations in gastric epithelial cells and T cells. Several families of vacA alleles have been de...
This study was designed to investigate the role of caspase-3/E-cadherin in Helicobacter pylori (H. pylori) -induced gastric epithelial apoptosis in cells, animal models and clinical gastritis patients. In cultured gastric mucosal epithelial cells, gastric glandular epithelial cells and C57BL/6 mice, H. pylori infection significantly induced apoptosis of gastric epithelial cells, down-regulated ...
We evaluated homeostatic mass control in non-neoplastic gastric epithelia under Helicobacter pylori (HP) infection in the macroscopically normal-appearing mucosa resected from the stomach with gastric cancer, immunohistochemically analyzing the proliferation, kinetics of stem cells and programmed cell death occurring in them. Ki67 antigen-positive proliferating cells were found dominantly in th...
Chronic inflammation caused by infection with Helicobacter pylori and autoimmune gastritis increases an individual's risk of developing gastric cancer. More than 90% of gastric cancers are adenocarcinomas, which originate from epithelial cells in the chronically inflamed gastric mucosa. However, only a small subset of chronic gastritis patients develops gastric cancer, implying a role for genet...
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