objective: helicobacter pylori has a well-established role in the development of gastric cancer. in vitro studies reveal increased proliferation of the gastric mucosa in the presence of h. pylori infection. it has been also shown that production of some cytokines, such as interleukin-1 beta (il-1b) is increased in h. pylori infection. in addition, il-1b increases proliferation of gastric epithe...

Objective: Helicobacter pylori has a well-established role in the development of gastric cancer. In vitro studies reveal increased proliferation of the gastric mucosa in the presence of H. pylori infection. It has been also shown that production of some cytokines, such as interleukin-1 beta (IL-1b) is in...

Morphological and histochemical study of the abomasal epithelium in camel (Camelus dromedarius) wascarried out by light and scanning electron microscopes. The lining of the abomasum was divided into fourregions, i.e. cardiac, pseudocardiac, fundic and pyloric. Our investigation revealed that the cardiac andpseudocardiac regions occupy a wide part of the abomasum in camel and it reaches approxim...

Animal studies showed that male gastric tissues respond more rapidly to Helicobacter pylori (H.pylori) infection but the possible mechanisms remained unclear. There is no data about gender specific activity of Androgen receptor (AR) as an independent unfavorable prognostic factor in gastric cancer and its interactions with H.pylori and angiogenesis in both genders. To compare the pathogenesis o...

morphological and histochemical study of the abomasal epithelium in camel (camelus dromedarius) wascarried out by light and scanning electron microscopes. the lining of the abomasum was divided into fourregions, i.e. cardiac, pseudocardiac, fundic and pyloric. our investigation revealed that the cardiac andpseudocardiac regions occupy a wide part of the abomasum in camel and it reaches approxim...

helicobacter pylori (h. pylori) is classified as a class i carcinogen. the low infection rate seen in developed countries (8.9%) compared with a high infection rate (52%-98%) in developing countries indicates a strong association between infection prevalence and socioeconomic status. adhesion of h. pylori to gastric epithelial cells is an important aggressive factor. one of the genes that encod...

Background & Objective: Gastric cancer is the second most frequent cause of cancer death worldwide, despite differences in incidence around the world. The majority of gastric cancer cases concern gastric adenocarcinoma, which has a fairly high 5-year survival rate when coupled with early-stage diagnosis. Versican, a member of the aggregating chondroitin sulfate proteoglycans fa...

Purpose: To investigate the effects of amygdalin on proliferation, motility and epithelial mesenchymal transformation (EMT) gastric cancer cells to elucidate operating mechanisms action.Methods: Gastric AGS were treated with (2.5, 5 10 mg/L). MTT colony formation assays used effect cell while wound healing Transwell also carried out determine its cells. Immunoblot process TGF-β/Smad pathway in ...

Objective(s): The present paper aims to review the studies describing the interactions between HopQ and CEACAMs along with possible mechanisms responsible for pathogenicity of Helicobacter pylori.Materials and Methods: The literature was searched on “PubMed” using different key words including Helicobacter pylori, CEACAM and gastric.<br ...

Various growth factors are suggested to be involved in gastric mucosal repair. Our previous studies have shown that exogenous hepatocyte growth factor (HGF) has a proliferative effect on gastric epithelial cells. In the present study, comparison of the maximum proliferative effects and the optimum concentrations of several growth factors revealed that HGF was the most potent mitogen for gastric...