نتایج جستجو برای: gelucire
تعداد نتایج: 73 فیلتر نتایج به سال:
Background and purpose: Solubility behavior of a drug is one of the key determinants of its oral bioavailability. The bioavailability may be enhanced by increasing the solubility and dissolution rate of drug by combining the drug with a hydrophilic carrier. Naproxen is a poor water non-soluble analgesic and anti- inflammatory drug. A possible way of overcoming the naproxen low aqueous solubilit...
Lamotrigine is used in the treatment of CNS disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. Lamotrigine belongs to biopharmaceutical classification systems, BCS class II (Low solubility & High permeability). In addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...
lamotrigine is used in the treatment of cns disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. lamotrigine belongs to biopharmaceutical classification systems, bcs class ii (low solubility & high permeability). in addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...
Objective: The aim of this study was to design and optimize lipid based beads for multiunit floating drug delivery ramipril.
 Methods: prepared by melt-solidification method. In the investigation 32 full factorial used investigate joint influence two formulation variable amount Gelucire (X1) Tween 20 (X2) as independent percentage release in 1 (Y1), 6 (Y2), 12 h (Y3) dependent variable. 43...
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