A procedure for reconstructing solid models of conventional engineering objects from a multiple-view, 3D point cloud is described. (Conventional means bounded by simple analytical surfaces, swept surfaces and blends.) Emphasis is put on producing accurate and topologically consistent boundary representation models, ready to be used in computer aided design and manufacture. The basic phases of o...

Ontologies facilitate the integration of heterogeneous data sources by resolving semantic heterogeneity between them. This research aims to study the possibility of generating a domain conceptual model from a given ontology with the vision to grow this generated conceptual data model into a global conceptual model integrating a number of existing data and information sources. Based on ontologic...

Numerous organizations face the need to develop highly con gurable systems with thousands of functionalities and variable subsystems. Feature Models (FMs) are a popular formalism for modeling and reasoning about con gurations of a system. As the manual construction or management of an FM is time-consuming, error-prone and not realistic for large software projects, automated operations for rever...

From general considerations of the basic physiological properties of the cell division cycle, we deduce what the dynamical properties of the underlying molecular control system must be. Then, taking a few hints from the biochemistry of cyclin-dependent kinases (the master regulators of the eukaryotic cell cycle), we guess what molecular mechanisms must be operating to produce the desired dynami...

In many areas of industry, it is desirable to create geometric models of existing objects for which no such model is available. This paper reviews the process of reverse engineering of shapes. After identifying the purpose of reverse engineering and the main application areas, the most important algorithmic steps are outlined and various reconstruction strategies are presented. Pros and cons of...

Part of the material the lecture is related with the PHENIX research project developed jointly by the University of Namur 1 and the BIKIT 2. The objective of the project is to develop an expert-system approach to database reverse engineering. Reverse engineering a piece of software consists in reconstructing its functional and technical documentation, starting mainly from the source text of the...

Reverse Engineering is a process fraught with imperfections. The importance of dealing with non-precise, possibly inconsistent data explicitly when interacting with the reverse engineer has been pointed out before. In this paper, we go one step further: we argue that the complete reverse engineering process must be augmented with a formal representation model capable of modeling imperfections. ...

Model Driven Engineering (MDE) received a lot of attention in the last years, both from academia and industry. However, there is still a debate on which basic concepts form the foundation of MDE. The Model Driven Architecture (MDA) from the OMG does not provided clear answers to this question. This standard instead provides a complex set of interdependent technologies. This paper is the first o...

OUTLINE Introduction Formal representation of GRNs An example of a GRN: The Lac Operon Hierarchies of GRN models: From probabilistic graphs to mechanistic models A guide to databases and knowledgebases on the internet Pathway Databases & Platforms Ontologies for GRN modeling Current Gene, Interaction, and Pathway Ontologies Whole­cell modeling platforms Ontology for modeling multi­scale and inc...