نتایج جستجو برای: hot plate method
تعداد نتایج: 1757156 فیلتر نتایج به سال:
Background and purpose: Histamine is a neurotransmitter present in the brain of mammals which produces its physiological effects on target cells by stimulation of three types of receptors H1, H2 and H3. Various reports nowadays indicate the role of histamine in reduction of pain transmission. This study was designed to determine the role of histamine receptors in reduction of pain. Mate...
Aim: To evaluate the analgesic activity of aqueous extract of S. hispida on thermal and chemical method induced pain in mice. Materials and methods: 48 Adult albino mice (Swiss strain) weighing 25-30 gm were selected. 24 animals were allocated to each experimental model, in each model there were 4 groups. The control group received vehicle (10 ml /kg, p.o), standard group aspirin (300 mg /kg, p...
The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...
The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...
The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...
Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...
Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...
The aqueous leaves extract of Ocimum gratissimum was investigated for anti-nociceptive and anti-inflammatory effects in mice and rats. The models used to study the effect on nociception are the acetic acid-induced abdominal constriction test, hot-plate method in mice. The anti-inflammatory effect was investigated employing the formalin-induced hind-paw oedema in rats. The extract caused a signi...
In this study, the analgesic, antipyretic and anti-inflammatory effects of the methanolic extract obtained from the leaves of Thunbergia coccinea Wall were investigated. Analgesic effect of MTC was evaluated by acetic acid –induced writhing, hot plate and tail flick method. Antipyretic activity of MTC was evaluated by yeast –induced hyperpyrexia in rats. The antiinflammatory activity was studie...
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