PURPOSE To compare various techniques of pterygium surgery including bare sclera, intraoperative mitomycin C application, conjunctival flap reconstruction, and conjunctival autografting technique. METHODS This study is designed to compare 4 currently used techniques in order to determine the complication and recurrence rates after pterygium exision. Included in the study were 77 eyes from 60 ...

Objective: To determine the effect of intravitreally administered bevacizumab, alone or as adjunct to mitomycin-C, after trabeculectomy on bleb survival and histology in rabbit eyes. Methods: An experimental, interventional, comparative, animal study consisting of 16 rabbit eyes underwent trabeculectomy, 8 of which were enhanced with intra-operative mitomycin-C. Eyes were randomized to receive ...

Objective (s): This study aimed at investigation of preparation and stability study of Mitomycin and Mitomycin loaded nanoliposems and efficacy of the combination of Mitomycin -loaded nanoliposomes and Curcumin versus Mitomycin in suppressing HTB-9 and L929 cell lines, in vitro.Materials and Methods: An HPLC method was validated based on Q2 (R1) International Conference on Harmonization (ICH) g...

BACKGROUND We report necrotizing scleritis as a serious complication of a cosmetic eye whitening procedure that involves the use of intraoperative and postoperative topical mitomycin C. FINDINGS This is a single case report. A 59-year-old Caucasian male with a history of blepharitis status post uncomplicated LASIK refractive surgery reported chronic conjunctival hyperemia for 15 years prior t...

PURPOSE Dacryocystorhinostomy (DCR) is widely accepted as the procedure of choice for surgical correction of lacrimal drainage system obstruction distal to common canaliculus in adulthood. The success rate of DCR has been reported to be from 63% to 99%. DCR failure has been attributed to membranous occlusion of the rhinostomy site caused by soft tissue scarring. More recently, use of mitomycin ...

PURPOSE To evaluate the long-term effects of intraoperative application of mitomycin C on the scleral thickness and the conjunctival epithelium at the surgical site of pterygium excision. DESIGN Prospective observational case series. PARTICIPANTS Twenty-four patients who underwent excision of primary pterygium with intraoperative mitomycin C in our department during the year 1996. METHODS...

Objective: To compare the success rate of trabeculectomy with and without Mitomycin C in lowering intraocular pressure. Design: Prospective, comparative, randomized, interventional study. Duration: Two years. Place: Department of Ophthalmology, Lady Reading Hospital, Peshawar. Material and Methods :This prospective study of 100 eyes of 80 patients of glaucoma was conducted from January 2005 to ...

PURPOSE To report the efficacy, safety, predictability and complications of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). METHODS This historical cohort study was performed on 1,250 eyes of 625 patients who underwent PRK using the Technolas 217 excimer laser machine by a single surgeon with intraoperative use of MMC 0.02% up to 2 minutes, depending on...