Background and Aim: Fungal rhinosinusitis (FRS) sets in following interactivity of fungi with Sino nasal tract when immune system is subdued. Due to varied clinical presentation of FRS with inconclusive evidence of imaging, mycological evaluation helps to identify and speciate the fungi .FRS can be diagnosed with biopsy tissue and/or deep nasal swabs. This study was undertaken to know risk fact...

the incidence of nosocomial fungal infections has increased dramatically during the past two decades as the consequence of continuous increase in the number of severely immunocompromised patients. this study was done to determine the presumptive sources of nosocomial fungal infections at the intensive care unit and transplant wards (in a university- based teaching hospital in tehran) during a 1...

Patients with HIV/AIDS can present with multiple types of fungal rhinosinusitis, fungal balls, granulomatous invasive fungal rhinosinusitis, acute or chronic invasive fungal rhinosinusitis, or allergic fungal rhinosinusitis (AFRS). Given the variable spectrum of immune status and susceptibility to severe infection from opportunistic pathogens it is extremely important that clinicians distinguis...

Fluconazole is commonly used both to prevent and to treat invasive neonatal Candida albicans infection. This drug is a potent, selective, triazole inhibitor of the fungal enzymes involved in ergosterol synthesis. It is largely excreted unchanged in the urine. In infants with a birth weight

Exophiala species are ubiquitous dematiaceous yeast-like fungi of the order Chaetothyriales that bear melanin-like pigment in their cell wall that is responsible for their dark color and is thought to be a major fungal virulence factor [1–3]. Among the agents of phaeohyphomycosis (cutaneous, subcutaneous, and invasive infections caused by dark-walled fungi), most human Exophiala infections are ...

EDITORIAL article Front. Cell. Infect. Microbiol., 14 July 2023Sec. Fungal Pathogenesis Volume 13 - 2023 | https://doi.org/10.3389/fcimb.2023.1227837

The incidence and prevalence of fungal infections in Russia is unknown. We estimated the burden of fungal infections in Russia according to the methodology of the LIFE program (www.LIFE-worldwide.org). The total number of patients with serious and chronic mycoses in Russia in 2011 was three million. Most of these patients (2,607,494) had superficial fungal infections (recurrent vulvovaginal can...

Nosocomial fungal infections have become increasingly common. This increase has been documented globally, i.e., in Europe [1], Asia [2,3], and North and South America [4,5]. In the United States, reports to the Centers for Disease Control and Prevention’s (CDC) National Nosocomial Infections Surveillance (NNIS) System document this increase in multiple clinical sites, including bloodstream, sur...

BACKGROUND Invasive fungal infections in neutropenic patients treated for haematological malignancies are associated with a high mortality rate and, therefore, require early treatment. As the diagnosis of invasive fungal infections is difficult, effective antifungal prophylaxis is desirable. So far, fluconazole has been the most commonly used. OBJECTIVE To assess the cost effectiveness of itr...