The retinoblastoma gene product, pRb, plays a crucial role in cell cycle regulation, differentiation and inhibition of oncogenic transformation. pRb and its closely related family members p107 and p130 perform exclusive and overlapping functions during mouse development. The embryonic lethality of Rb-null animals restricts the phenotypic analysis of these mice to mid-gestation embryogenesis. We...

abstract this study has been investigated viewpoint of border cooperative society members of their activities in khorasan razavi, first step was evaluated satisfaction's member of performance indicators cooperatives, next step each of the indicators were prioritized according to members satisfaction using entropy method. finally, the results of these two methods have been compared together. dat...

The mouse skin carcinogenesis represents one of the best models for the understanding of malignant transformation, including the multistage nature of tumor development. The retinoblastoma gene product (pRb) plays a critical role in cell cycle regulation, differentiation, and inhibition of oncogenic transformation. In epidermis, Rb-/- deletion leads to proliferation and differentiation defects. ...

urbanization agglomeration that is named jacobs externalities, refers to the role of economic diversification in urban. localization agglomeration, marshal-arrow-romer (mar) externalities, is related to the concentration of firms activated in a special industry within a specified place. the purpose of this research is to explore the impact of different types of agglomeration economies on employ...

the main objective of this paper is to study the relationship between the energy consumption (energy use intensity), economic growth, and co2 emission in iran. to that end, we use time series data of iran during 1967–2004. in order to examine the long-run relationship among these variables, the johanson-juselius cointegration method is used along with vecm. the main finding of this study shows ...

The present paper thoroughly explores second-best efficient allocations in an adverse selection insurance economy. We start from a natural extension of the classical model, assuming less than perfect risk perceptions. We propose first and second welfare theorems, by means of which we describe efficiencyenhancing policies. Notions of weak and strong adverse selection are promising for interpreti...

The liver is susceptible to such oxidative and metabolic stresses as ischemia-reperfusion (I/R) and fatty acid accumulation. Probiotics are viable microorganisms that restore the gut microbiota and exert a beneficial effect on the liver by inhibiting bacterial enzymes, stimulating immunity, and protecting intestinal permeability. We evaluated Lactobacillus paracasei F19 (LP-F19), for its potent...

We define as South Asian countries those countries that start with Iran and end with Bangladesh in Asia. Wethen use export statistics in terms of revealed comparative advantage (RCA) for 14 industrial sectors tomeasure distances of export capabilities for these countries in relation to the “Western” developed and EastAsian countries. Statistical methods such as multidimensional scaling and ...