results the results reveal that pq can decrease mitochondrial viability, deplete gsh content, increase mitochondrial ros formation, and enhance lpo and mitochondrial membrane damage. the pretreatment of mitochondria with ng has the ability to reduce the toxic effects of pq in isolated mitochondria. background paraquat (pq) is a dipyridyl herbicide that sustains damage due to redox cycling. an i...

Arsenic exposure mainly through food and water has been shown to be associated with increased incidence of numerous cancers and non-cancer harmful health. It is also used in cancer chemotherapy and treatment of several cancer types due to its apoptogenic effects in the various cancer and normal cell lines. We have already reported that liver is the storage site and important target organ in As ...

arsenic exposure mainly through food and water has been shown to be associated with increased incidence of numerous cancers and non-cancer harmful health. it is also used in cancer chemotherapy and treatment of several cancer types due to its apoptogenic effects in the various cancer and normal cell lines. we have already reported that liver is the storage site and important target organ in as ...

background: the ultrastructural analysis of cultured follicles could direct us to understand subcellular changes during in vitro culture. objective: this study was done to verify the ultrastructural characteristics of in vitro cultured mouse isolated preantral follicles in co-culture system in the presence and absence of leukemia inhibitory factor (lif) materials and methods: mechanically isola...

conclusions our results suggest that h. parva and h. oculata may be promising therapeutic candidates for the treatment of hcc, following further confirmatory in vivo experiments and clinical trials. results our results showed that h. parva methanolic extracts (250, 500, and 1000 µg/ml) and h. oculata methanolic extracts (200, 400, and 800 µg/ml) increased reactive oxygen species (ros) formation...

anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet ccl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). group i (control), while group ii was given ccl4 (3 ml /kg/day, ip). animals of groups iii received only propofol (10 mg/kg/day, ip). group iv was given propofol+ ccl4. group v was admin...

Industrial wastewater is of global concern due to its severe effects on the environment. Compared with municipal wastewater, industrial wastewater generally contains the high concentration of toxic or no biodegradable pollutants. In recently year, scientific showed that scallop could filtration wastewater. Therefore, it was decided to determine the mechanistic toxicity of wastewater contained N...

Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds used as antioxidant agents. This study aimed to investigate compare the effects fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials Methods: In this regard, mitochondria were isolated from 27 male Wistar rats (220-250 g). The cultured different doses f...