Introduction: Visceral leishmaniasis (kala-azar) caused by Leishmania donovani and transmitted by the sand-fly Phlebotomus martini is endemic in certain foci in north-eastern Uganda where it is thought to be confined to Pokot county, Amudat district. Amudat hospital records (April 1998-March 1999) indicated that kala-azar accounted for about 17% of hospital in-patients. However the actual preva...

BACKGROUND Kala bhat (Black soybean) is an important legume crop in Uttarakhand state, India, due to its nutritional and medicinal properties. In the current study, the genetic variabilities present in Kala bhat were estimated using SSR markers and its variability was compared with other improved soybean varieties cultivated in Uttarakhand state, India. RESULTS Seventy-five genotypes cultivat...

their spleens by " spleen puncture." Certainly, most of the patients whom we see are sent to us . from the Medical College Hospital Out-patient Dispensary and by local practitioners because they have symptoms which suggest kala-azar. On the other hand, of the patients who are eventually diagnosed kala-azar in the Medical College Hospital, more than half have been admitted not as kala-azar patie...

In this study 4 patients were post-kala-azar dermal leishmaniasis (PKDL), whose lesions were similar to those of lepromatous and borderline leprosy, are described. In 2 patients there was no previous history of kala-azar but they were residents of an area of known endemic kala-azar. Lack of proper clinical and laboratory assessment was behind the failure to diagnose PKDL. Consequently the patie...

Concomitant skin lesions in visceral leishmaniasis (VL) or kala-azar are rare, being more common the description of post-kala-azar dermal leishmaniasis occurring post treatment of kala-azar. Skin lesions caused by Leishmania donovani are frequently seen in the aids-VL co-infection. In Brazil cutaneous or mucosal forms of tegumentary leishmaniasis concomitant with aids are more commonly register...

thirty eight patients with visceral leishmaniasis were reviewed, age ranged from 2 months to 10 years, 74% above 3.5 y, with 24% affection in infants (7 to 12 m), with slight male predilection. all the patients had weight loss, splenomegaly and hepatomegaly, 97% with fever, 92% had positive serology and 63% had positive bone marrow findings. a few patients presented with atypical clinical findi...

in a descriptive analytical study in six villages in meshkin shahr area, the important endemic focus of kala-azar in northwest iran, a kap study was carried out on various aspects of kala-azar in a total of 245 young mothers selected randomly and interviewed the results of the present investigation showed that 93.5% of the mothers were illiterate and only 2.4% of them had acceptable knowledge a...

After two peaks of epidemic of Kala Azar, one in 1977 with 100,000 cases(l) and another in 1991-92 with 250,000 cases(2), the disease continues to be endemic in North Bihar The first line drug sodium antimony shbogluconate (SAG) used in the dosage of 20 mg/kg body weight daily for 30 days(3) or 40 days(4) has become less effective and a number of patients are unresponsive to the drug(5) Oral Fl...

Pentavalent antimonials (SbV) have been successfully used for treatment of kala-azar since last six decades. Since 1970s its conventional dosages have failed to achieve with 60 per cent unresponsiveness reported with WHO regimen in Bihar (India). Pentamidine initially used as a second line of drug, acquired resistance (25%) even with prolonged dosage. Newer oral drug miltefosine is a potent ant...