background and objective: uterus of rat with polycystic ovary (pco) may show pathological features. we provided pathological evidence for the rat uterus with no-induced pco.    materials and methods: wistar rats (weighing 200-250 g) were kept diestrous to receive l-arginine (50 mg/kg) intraperitoneally (i.p.) for 9 days/once a day. control group solely received saline (1 ml/kg, 9 days/once per ...

Introduction: Nitric oxide (NO), as a free radical, involves in several physiologic functions in GI tract such as nerve impulse transmission and vascular tonicity regulation. Nitric oxide synthase (NOS) is the enzyme for the production of NO from L-Arginine which in turn inhibits by L-NGNitroarginine Methyl Ester (L-NAME). In the current work, we aimed to evaluate morphometric analysis of...

Introduction: The aim of the present study was to evaluate the effect of exercise training and L-arginine supplementation on oxidative stress and systolic ventricular function in rats with myocardial infarction (MI). Methods: Four weeks after the surgically-induced MI, 40 male Wistar rats were randomly assigned to the following 4 groups (n=10): MI-sedentary control (Sed) MI-exercise (Ex) MI-...

Introduction: This study was conducted to determine the possible beneficial results of L-arginine on prefrontal cortex of rats which impressed by immobilization stress to define the synchronous impression of stress and nitric oxide (NO) on evolution of prefrontal cortex of rats after birth. Methods: Forty-eight one month, male Wistar rats were divided into two groups: stressed and ...

background: role of nitric oxide (no) on expression of morphine conditioning using a solely classic task has been proposed previously. in this work, the involvement of no on the expression of opioid-induced conditioning in the task paired with an injection of naloxone was investigated. methods: conditioning was established in adult male wistar rats (weighing 200-250 g) using an unbiased procedu...

objective: tthe objective of this study was to assess the efficacy and safety of sx (combination of yohimbine and l-arginine) in the treatment of erectile dysfunction (ed) methods: this trial was a 4-week, double blind study of parallel groups of patients with mild to moderate ed. forty married male patients with ed of mild-to-moderate severity were screened for the study entry;among them, thos...

Introduction: The role of ovarian hormones and nitric oxide (NO) on oxidative damage in brain tissues as well as learning and memory has been widely investigated.The present study was carried out to evaluate the effect of the precursor of NO, L-Arginine on learning and brain damage due to oxidative stress in ovariectomized (OVX) rats.Methods: Thirty -two rats were divided into four groups: 1) S...