نتایج جستجو برای: l929
تعداد نتایج: 1304 فیلتر نتایج به سال:
زمینه و هدف: سیاه دانه (nigella sativa) گیاهی ازتیره آلاله٬ علفی، یک ساله یا پایا است. ترکیبات این گیاه دارای خواص ضد سرطانی هستند. این مطالعه با هدف بررسی اثر سایتوتوکسیک و آپوپتوتیک عصاره الکلی سیاهدانه بر روی رشد سلول های سرطانی کلیه انسان رده achn و سلول های غیر سرطانی سالم رده l929 انجام شد. روش بررسی: در این مطالعه تجربی غلظت های مختلف عصاره الکلی سیاهدانه در محیط کشت، روی سلول های achn و...
Tumor necrosis factor (TNF)-alpha induces caspase-independent cell death in the fibrosarcoma cell line L929. This cell death has a necrotic phenotype and is dependent on production of reactive oxygen species (ROS) in the mitochondria. To identify genes involved in this TNF-induced, ROS-dependent cell death pathway, we utilized retrovirus insertion-mediated random mutagenesis to generate TNF-res...
Coxiella burnetii, the agent of Q fever in man and of coxiellosis in other species, is a small, dimorphic, obligate intracellular bacterium, sheltered within large, acidified, and hydrolase-rich phagosomes. Although several primary and established cell lines, macrophage-like cells, and primary macrophages from other species have been infected with C. burnetii, the infection of mouse primary mac...
It is well known that mouse uterine 24p3 protein, is an acute phase protein, secreted from the L929 cell line, and that it will be induced by the dexamethasone stimulation of the cell. We investigated the possible effects of 24p3 protein on the L929 cell line, by observing its morphological change, ROS increase and viability decrease, by the process of culturing in a 24p3 protein-supplemented m...
Autophagy has diverse biological functions and is involved in many biological processes. The L929 cell death induced by the pan-caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-(OMe)-fluoromethyl ketone (zVAD) was shown to be an autophagy-mediated death for which RIP1 and RIP3 were both required. It was also reported that zVAD can induce a small amount of TNF production, which was shown to be re...
The Nine Mile, S Q217, and Priscilla isolates, representative of the three major genetic groups of Coxiella burnetii, are known to differ in their susceptibilities to antibiotics. Mechanisms potentially responsible for these differences were investigated. Accumulation of antibiotics by infected L929 cells and purified isolates was measured. In addition, C. burnetii plasmid-transformed Escherich...
The physical behaviors of stationary cells, such as the morphology, motility, adhesion, anchorage, invasion and metastasis, are likely to be important for governing their biological characteristics. A change in the physical properties of mammalian cells could be an indication of disease. In this paper, we present a silicon-nanowire-array based technique for quantifying the mechanical behavior o...
زﻣﯿﻨﻪ وﻫﺪف: وﯾﺮوس EMCVاز ﺧﺎﻧﻮاده ﭘﯿﮑﻮرﻧﺎوﯾﺮﯾﺪه و از ﺟﻨﺲ ﮐﺎردﯾﻮوﯾﺮوس ﻫﺎ ﺑﻮده واز ﻧﺘﺎﯾﺞ ﺗﮑﺜﯿﺮ اﯾﻦ وﯾﺮوس در رده ﻫﺎﯾﯽ ﻧﻈﯿﺮ A549 ، L929 در ﻣﻄﺎﻟﻌﺎﺗﯽ ﻧﻈﯿﺮ ﺳﻨﺠﺶ ﻣﻘﺎدﯾﺮ اﯾﻨﺘﺮﻓﺮون ﻫﺎ وﺗﻌﯿﯿﻦ ﻓﻌﺎﻟﯿﺖ زﯾﺴﺘﯽ آﻧﻬﺎ وﺗﺤﻘﯿﻘﺎت ﻣﺘﻌﺪد دﯾﮕﺮ ﺑﻪ ﮐﺜﺮت ﺑﻪ ﮐﺎر ﮔﺮﻓﺘﻪ ﺷﺪه اﺳﺖ. اﯾﻦ ﺗﺤﻘﯿﻖ ﺑﺎ ﻫﺪف ﺑﺮرﺳﯽ ﻣﻘﺎﯾﺴﻪ ای ﺗﮑﺜﯿﺮ وﯾﺮوس EMCV در دو رده ﺳﻠﻮﻟﯽ A549 ، L929 ﺑﺮای ﺗﻌﯿﯿﻦ ﭘﺎﯾﻪ ﺳﻠﻮﻟﯽ ﻣﻨﺎ...
GİRİŞ ve AMAÇ: Akrep zehirleri çeşitli kimyasal maddelerin oluşturduğu oldukça kompleks heterojen karışımlardır. Bu çalışmada, bir akrep türü Mesobuthus gibbosus (Brullé, 1832) (Scorpiones: Buthidae)’un ham zehrinin kanser hücre hatları üzerine sitotoksik antiproliferatif etkileri araştırılmıştır. YÖNTEM GEREÇLER: M. gibbosus’dan elde edilen zehrin iki insan hattı (MCF-7 meme kanseri A549 akciğ...
زمینه و هدف: سیاه دانه (Nigella sativa) گیاهی ازتیره آلاله٬ علفی، یک ساله یا پایا است. ترکیبات این گیاه دارای خواص ضد سرطانی هستند. این مطالعه با هدف بررسی اثر سایتوتوکسیک و آپوپتوتیک عصاره الکلی سیاهدانه بر روی رشد سلول های سرطانی کلیه انسان رده ACHN و سلول های غیر سرطانی سالم رده L929 انجام شد. روش بررسی: در این مطالعه تجربی غلظت های مختلف عصاره الکلی سیاهدانه در محیط کشت، روی سلول های ACHN ...
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