With the object of improving the effectiveness of a malignant melanoma's treatment and a patients' quality of life, there is a serious need to identify new anticancer compounds, for example, among naturally derived compounds such as sodium butyrate. The aim of this study was to assess the combined impact of carboplatin (C) and sodium butyrate on the B16 melanoma viability by in vitro. B16 cell ...

Pendahuluan: Jumlah kasus demam berdarah yang berfluktuasi tiap tahunnya disebabkan pengendalian vektor (Aedes aegypti) berbasis insektisida kimiawi belum optimal. Banyak enggan menggunakan karena berbagai efek samping dapat ditimbulkan. Diperlukan alternatif lain digunakan yaitu dari tumbuhan. Salah satu tumbuhan berpotensi sebagai larvasida adalah daun sirih merah. Metode: Penelitian ini bert...

Efficacy of 25 essential oils was screened against filarial vector, Culex quinquefasciatus, for their larvicidal and knockdown effects in a preliminary study. Of these, 8 oils viz. calamus oil, cinnamon oil, citronella oil, clove oil, eucalyptus oil, lemon oil, mentha oil and orange oil exhibited 100% larvicidal activity at 1000 ppm and 100% knockdown effect at 10% concentration. These 8 oils w...

Second generation Bt crops (insect resistant crops carrying Bacillus thuringiensis genes) combine more than one gene that codes for insecticidal proteins in the same plant to provide better control of agricultural pests. Some of the new combinations involve co-expression of cry and vip genes. Because Cry and Vip proteins have different midgut targets and possibly different mechanisms of toxicit...

The present study has been conducted to investigate the effect of insect growth regulator BAY SIR 8514 on chitin and chitinase enzymes of 2 in star of Spodoptera littoralis larvae, the effect of sublethal doses, LC 25, LC 50 and LC90 shows a significant effect on antifeedant index, on the other hand larval treatment with the tested IGR doses revealed, certain histo-pathological symptoms such as...

The house fly, Musca domestica, is a very significant pest due to transmitting of various human and animal pathogenic diseases. In a response to environmental threats of chemical insecticides, toxic and biochemical effects of a relatively new plant extracts of willow (Salix aegyptiaca L.) and chasteberry (Vitex agnus-castus L.) comparing with NeemAzal T/S were studied on 3 larval instar of M. d...

With a goal of minimal application of environmentally hazardous chemical insecticides, the larvicidal activity of cypermethrin was studied alone and in combination with the root extract of Solanum xanthocarpum against anopheline larvae. Petroleum ether extract was observed to be the most toxic, with LC,, of 1.41 and 0.93 ppm and LC90 of 16.94 and 8.48 ppm at 24 and 48 hours after application, r...

The insecticidal activity of essential oils isolated from two species of Origanum (Origanum onites L. and Origanum minutiflorum (O. Schwarz and P.H. Davis) (Labiate)) was investigated against 3rd and 4th instar larvae of the mosquito, Culex pipiens L. (Diptera: Culicidae). The LC50 and LC90 values were 24.8 and 61.3 ppm, and 73.8 and 118.9 ppm, respectively. This activity was attributed to the ...

A successful attempt of using sodium salt of a water- insoluble larvicide, as an alternative to the use of solutions of such larvicides in acetone and water, for the larvicidal studies is made, in the present study biochanin - A an isoflavone isolated from the flowers of Dalbergia sissoides (grah) when assessed for larvicidal study as its sodium salt on the fourth instar larvae of Culex quinque...