Question Are levo acetyl methadol (LAAM) and buprenorphine as effective as methadone for substitution treatment of opioid dependence? Participants: 220 people categorised as opioid dependent by DSM-IV; 1 groups similar on demographics and drug use history. Exclusion criteria were medical and psychiatric illness requiring long-term medication, and pregnancy. Interventions: (i) Levo acetyl methad...

Levofloxacin (Levo), a second generation fluoroquinolone, has both clinical and environmental relevance. Therefore, the implementation of fast, robust and cost effective techniques for its monitoring is required. Here, its spectroscopic characterization and its detection in aqueous environment were carried out using surface enhanced Raman spectroscopy combined with droplet based microfluidics. ...

Dobutamine, a structural relative of dopamine, acts directly on alphaand beta-adrenergic receptors without the release of norepinephrine or activation of dopaminergic receptors. For clinical use, dobutamine is a racemic mixture of a levo-isomer acting as a potent alpha-1 agonist and a dextro-isomer counterbalancing this effect as an alpha-1 antagonist. Both isomers are complete beta-receptor ag...

A novel series of double hydrogen bonded liquid crystals have been isolated. Hydrogen bond was formed between non mesogen chiral ingredient levo tartaric acid (LTA) and mesogenic undecyloxy benzoic acids (11BA) Thermal and electrical properties exhibited by levo tartaric acid and undecyloxy benzoic acid (LTA+11BA) were discussed. Interesting feature of the present investigation was observation ...

Thyroid hormone resistance (THR) is a rare syndrome of reduced end organ sensitivity. Patients with THR have elevated serum free thyroxine (FT4), free triiodothyronine (FT3), but normal or slightly elevated serum thyrotropin values. The characteristic clinical feature is goitre without symptoms and metabolic consequences of thyroid hormone excess. THR can be classified on the basis of tissue re...