Aim: Determine the effect of dietary fats with different fatty acid composition on biosynthesis oleic and its metabolic precursors in liver .
 Methods: High linoleic sunflower oil (HLSO), high (HOSO) palm (PO) were used. Rats fed a semi-synthetic fat-free diet (FFD) fat diets containing 5 % above oils (instead starch) for 30 days. Liver lipids divided into 3 fractions: neutral (NL), phosph...

Obesity is a chronic multifactorial disease characterized by excess adiposity. Adipose tissue hypertrophy favors lipid deposition in ectopic tissues, such as the liver, which development of metabolic dysfunction-associated fatty liver (MAFLD), excessive accumulation lipids cytoplasm hepatocytes (fatty liver). Triglyceride overload observed obesity associated with inflammation and insulin resist...

Background: Non-alcoholic fatty liver disease (NAFLD) constitutes a global pandemic. An intricate network among cytokines and lipids possesses a central role in NAFLD pathogenesis. Red blood cells comprise an important source of both cytokines and signaling lipids and have an important role in molecular crosstalk during immunometabolic deregulation. However, their role in NAFLD has not been tho...

The liver is a major metabolic organ, essentially controlling glucose and fat metabolism. Because lipids are water-insoluble, they need to be transported in the circulation in association with proteins in the form of lipoproteins. These lipoproteins play a key role in the absorption and transport of dietary lipids by the small intestine, in the transport of lipids from the liver to peripheral t...

To evaluate the effect of feeding thermally oxidized vegetable oils and animal fats on growth performance, liver gene expression, and liver and serum fatty acid and cholesterol concentration in young pigs, 102 barrows (6.67 ± 0.03 kg BW) were divided into 3 groups and randomly assigned to dietary treatments in a 4 × 3 factorial arrangement. The main factors were lipid source (n = 4; corn oil [C...

3. i n the liver triglycerides from the control group-the C,, and C,, polyenoic fatty acids constituted 33 % of the total fatty acids. The liver triglyceride concentration in the low-fat group was lower and the concentration of the long-chain polyenoic fatty acids in this fraction was zo yo of the control value. The milk fatty acids from the low-fat group contained only 3 3 % as much of the C1,...

Background: Non-alcoholic fatty liver disease (NAFLD) is increasingly a common disease which is created by the accumulation of fat in the liver. About 20% of adults and 5% of children suffer from this disease. In some studies, half of obese children had fatty liver disease and approximately 90% of the patients with fatty liver were obese. The aim of this study was to evaluate fatty liver diseas...

Oral administration of vitamin A (30,000 IU daily for 2 days) to young rats caused a marked increase in hepatic glycogen, cholesterol, and glycerides, while hepatic phospholipid content remained almost unaltered. In an examination of the pathogenesis of the lipid accumulation, it was found that more glucose-(14)C was incorporated into liver lipids in vitamin A-fed rats, whereas incorporation of...