introduction: major depressive disorder is a common mental condition associated with substantial morbidity and economic burden. approved by the fda in september 2013 for treatment of episodes of major depressive disorder, vortioxetine is one of the newer options available in this important area of therapeutics. materials and methods: a comprehensive literature search (pubmed, the cochrane libra...

sheehan’s syndrome or simmond’s disease is a rare endocrine disorder seen in clinical practice. the clinical spectrum is diverse and a high index of suspicion together with a good clinical acumen and proper diagnostic approach helps in early diagnosis and prompt treatment of this endocrinopathy. sheehan’s syndrome presenting as a major depressive disorder finds less mention in the literature. t...

objective: given that the topic of bipolar disorder overdiagnosis has been relatively neglected in the literature and considering its significance in psychiatric training. the present study was conducted through an objective structured clinical examination (osce) on psychiatric residents to assess the validity of their clinical diagnosis. methods: twenty forth residents participated in the exam...

aim and background: efficacy of mindfulness based cognitive therapy and traditional cognitive behavior therapy in reduction of over generality in autobiographical memory test of patients with major depressive disorder in 2007 is considered in this study. method and materials: this clinical-experimental study was carried out on 90 patients randomly selected from 160 cases refering to tehran univ...

background: major depressive disorder is a mental disorder characterized by a pervasive and persistent low mood that is accompanied by low self-esteem and loss of interest or pleasure in normally enjoyable activities. depression is associated with multiple immunological disorders. aim of the present study was to determine correlation between percentage of circulating nk cells and major depressi...