نتایج جستجو برای: maternal serum screening test
تعداد نتایج: 1364594 فیلتر نتایج به سال:
BACKGROUND Down syndrome is one of the most important causes of mental retardation in the population. In the absence of prenatal screening and diagnosis, prevalence at birth in the United States would currently exceed 1:600. The purpose of prenatal screening is to identify those women at the increased risk for an affected pregnancy and to maximize the options available to these women. TESTS A...
OBJECTIVES Undetectable maternal serum unconjugated estriol levels in the second-trimester screening test have been associated with congenital pathology and an adverse pregnancy outcome. We reviewed outcomes of pregnancies with undetectable levels of estriol (<0.25 ng/ml) in the triple-marker screening test and assessed the clinical value of this finding. METHODS We studied estriol values in ...
BACKGROUND The aim of this study was to evaluate the interrelationships between maternal serum leptin level and body mass index (BMI) at different gestational ages or during the whole pregnancy. METHODS A total of 374 blood samples were obtained from 114 pregnant women when they visited the prenatal clinic for registration, Down syndrome screening test, 50 g oral glucose challenge test, hepat...
Background: The maternal serum alpha-fetoprotein test (MSAFP) was developed to screen for neural tube defects. Little is known about the adoption of the MSAFP test. This study examines the effect of provider specialty and geographic location and patient insurance status on MSAFP test use in Washington State. Methods: We conducted a retrospective cohort study of MSAFP use in low-risk obstetric p...
BACKGROUND The triple test serum markers for Down's syndrome screening may be altered because of various conditions other than chromosomal trisomies. OBJECTIVES To assess the profile of mid-trimester triple test serum markers in a cohort of women treated with low molecular weight heparin (LMWH) for thrombophilia since the first trimester. METHODS Women with inherited or acquired thrombophil...
Introduction: Prenatal maternal serum AFP screening tests have some inherent false positive and false negative results. For NTDs Screening test (FTS) false positive rate (FPR) is about 1% and false negative rate (FNR) is 20%. A false positive result encourages by Anomaly scan and invasive diagnostic procedures (that poses lots of stress on women, too), while a false negative result lead to a N...
OBJECTIVE To investigate whether measurement of maternal serum placental growth factor (PLGF) can improve the performance of first-trimester combined screening for trisomy-21 by fetal nuchal translucency (NT) thickness and serum free β-human chorionic gonadotropin (β-hCG) and PAPP-A. METHODS In singleton pregnancies attending for routine care, serum PLGF, free β-hCG and PAPP-A were measured a...
BACKGROUND Although maternal serum alpha-fetoprotein (MSAFP) is a highly sensitive marker for certain congenital malformations such as open neural tube and ventral wall defects, its usefulness as a screening test for fetal hydrocephalus is uncertain. We wished to determine the distribution of maternal serum alpha-fetoprotein levels associated with fetal hydrocephalus in a population-based scree...
OBJECTIVE To investigate the value of maternal serum placental protein 13 (PP-13) measurement and uterine artery Doppler during first-trimester screening in the prediction of early pre-eclampsia. METHODS This was a nested case-control prospective study of pregnancies at 11 + 0 to 13 + 6 weeks of gestation. The pulsatility index (PI) of blood flow in the uterine arteries and the maternal serum...
OBJECTIVE To estimate the value of first or second trimester placental growth factor (PlGF) as an additional antenatal screening marker for Down syndrome. DESIGN Nested case-control study. SETTING Antenatal screening service. POPULATION OR SAMPLE 532 Down syndrome pregnancies and 1,155 matched unaffected pregnancies. METHODS Stored maternal serum samples (-40°C) were assayed for PlGF. M...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید