A cryptic multidrug resistance (MDR) system in Stenotrophomonas maltophilia, the expression of which is selectable by tetracycline, is described. Tetracycline resistance was the consequence of active efflux of the antibiotic, and it was associated with resistance to quinolones and chloramphenicol, but not to aminoglycosides or beta-lactam antibiotics. MDR is linked to the expression of an outer...

The sensitivities of gonococcal isolates to six antibiotics were determined for gonococci isolated in Philadelphia in 1972. The degree of association between susceptibilities to any two antibiotics was determined (coefficient of correlation). The correlation between penicillin and tetracycline (r = 0.75) was almost as good as that between two penicillins, penicillin G and ampicillin (r = 0.85),...

Ten out of fifty fresh and refrigerated samples of shrimp (Litopenaeus vannamei) collected from retailers in Natal (Rio Grande do Norte, Northeastern Brazil) tested positive for Vibrio parahaemolyticus. The Kanagawa test and multiplex PCR assays were used to detect TDH and TRH hemolysins and the tdh, trh and tlh genes, respectively. All strains were Kanagawa-negative and tlh-positive. Antibioti...

background blood infections are an extensive range of disorders that can vary from limited bacteremia to fatal septicemia. bacteremia refers to the transient presence of a bacterium in the bloodstream. a delay in the diagnosis and treatment of sepsis can cause mortality, with a 20% - 50% prevalence rate. objectives due to the changing patterns of antibiotic resistance, as well as differences in...

The evolution and spread of antibiotic resistance depends on the antibiotic pressure exerted in the microbial environment. Selective effects occur in selective compartments, where particular antibiotic concentrations result in a differential growth rate of resistant bacterial variants. This may happen even at very low antibiotic concentrations able to select low-level-resistant bacteria. When m...