background: it is now well-demonstrated that histone demethylases play an important role in developmental controls, cell-fate decisions, and a variety of diseases such as cancer. lysine-specific demethylase 5d (kdm5d) is a male-specific histone demethylase that specifically demethylates di- and tri-methyl h3k4 at the start site of active genes. in this light, the aim of this study was to invest...

Considering the network structure is one of the new approaches in studying stochastic PERT networks (SPN). In this paper, planar networks are studied as a special class of networks. Two structural reducible mechanisms titled arc contraction and deletion are developed to convert any planar network to a series-parallel network structure. In series-parallel SPN, the completion time distribution f...

the probable lack of some arcs and nodes in the stochastic networks is considered in this paper, and its effect is shown as the arrival probability from a given source node to a given sink node. a discrete time markov chain with an absorbing state is established in a directed acyclic network. then, the probability of transition from the initial state to the absorbing state is computed. it is as...

a shortest path problem is a practical issue in networks for real-world situations. this paper addresses the fuzzy shortest path (fsp) problem to obtain the best fuzzy path among fuzzy paths sets. for this purpose, a new efficient algorithm is introduced based on a new definition of ideal fuzzy sets (ifss) in order to determine the fuzzy shortest path. moreover, this algorithm is developed for ...

technologies and various media have affected social institutions such as family and causeshape changes in relationships within the family. one of the means of communication that are easilyand widely used in the household is internet. with the entrance of media, especially the internet tothe family, changes in personal, social, public and private relationships are occurred. the use ofsocial netw...

here we consider the p-center problem on different types of fuzzy networks. in particular, we are interested in the networks with interval and triangular fuzzy arc lengths and vertex-weights. a methodology to obtain the best satisfaction level of the decision maker who wishes to reduce the cost within the tolerance limits is proposed. illustrative examples are provided.

there are three major strategies to form neural network ensembles. the simplest one is the cross validation strategy in which all members are trained with the same training data. bagging and boosting strategies pro-duce perturbed sample from training data. this paper provides an ideal model based on two important factors: activation function and number of neurons in the hidden layer and based u...

the present paper aims to explore the role of health research networks (hrn) in facilitating and expedite achieving the prospects for goals of health research based on the visions of iran by 2025.aiming to the main function of hsr to achieve the targeted conducting of health sciences research; more cooperation and coordination between health science researchers; avoid parallel investigations; a...