TRIAL SPONSOR Bangor University, Brigantia Building, College Road, Bangor, LL57 2AS, UK INTRODUCTION: The COPING parent online universal programme is a web-based parenting intervention for parents of children aged 3-8 years with an interest in positive parenting. The programme focuses on strengthening parent-child relationships and encouraging positive child behaviour. This trial will evaluate ...

Objective(s): Polyethylenimine (PEI) is one of the most widely used polymers in gene delivery. The aim of this study was to modify PEI by replacing some of its primary amines with Brevinin 2R (BR-2R) peptide in order to increase the efficiency of gene delivery.Materials and Methods: Polyethylenimine was modified by BR-2R peptide by two d...

Background Recent British National Health Service (NHS) reforms, in response to austerity and alleged ‘health tourism,’ could impose additional barriers to healthcare access for non-European Economic Area (EEA) migrants. This study explores policy reform challenges and implications, using excerpts from the perspectives of non-EEA migrants and health advocates in London.   Methods A qualitative ...

NHS Blood and Transplant; Imperial College Healthcare NHS Trust, London; University College Hospitals NHS Trust; Serious Hazards of Transfusion, NHS Blood and Transplant, Manchester/TTF member; Royal Hospital for Sick Children, Glasgow; NHS Blood and Transplant, Manchester; St. Mary’s Hospital, Manchester/University of Manchester; Royal Brompton Hospital, London; Mater Research Institute, Unive...

Nance-Horan syndrome (NHS) is an X-linked developmental disorder, characterized by bilateral congenital cataracts, dental anomalies, facial dysmorphism and mental retardation. Null mutations in a novel gene, NHS, cause the syndrome. The NHS gene appears to have multiple isoforms as a result of alternative transcription, but a cellular function for the NHS protein has yet to be defined. We descr...

Despite fiscal stress, public confidence in the National Health Service (NHS) remains strong; privatisation has not hollowed out the service. But if long term challenges are to be overcome, pragmatism not rhetoric should be the guide.

1. UK National External Quality Assessment Service 2 Department of Haematology, University Hospitals of Leicester 3. NHS Blood and Transplant & University Hospitals Bristol NHS Foundation Trust 4. Institute of Biomedical Scientists and NHS Blood and Transplant 5. University Hospitals of Leicester 6. International Blood Group Reference Laboratory, NHS Blood and Transplant. 7. Barts Health NHS Tr...

this commentary on the editorial ‘the politics and analytics of health policy’ by professor calum paton focuses on two issues. first, it points to the unclear links between ideas, ideology, values, and discourse and policy, and warns that discourse is often a poor guide to enacted policy. second, it suggests that realism, particularly ‘programme theory’ are useful tools for health policy analys...

The paper investigates the short run responsiveness of National Health Service (NHS) nurses’ labour supply to changes in wages of NHS nurses relative to wages in outside options available to nurses, utilising the panel data aspect of the Annual Survey of Hours and Earnings. We find the short run responsiveness of NHS nurses’ labour supply to the relative wage of NHS nurses is positive and stati...

When the mathematician Charles Babbage (1791–1871) published Passages from the life of a philosopher in 1864, he included a chronological list of 80 numbered ‘Papers which he has from time to time printed . . .’. The authors propose two, as yet unattributed, important additions to the Babbage bibliography. These papers, ‘Observations on the present State of the Mathematical Sciences in Great Br...