background and aims. the role of cytokines in the immunopathogenesis of oral lichen planus (olp) has received much attention. the aim of this study was to evaluate the serum levels of tnf-α and tgf-β in patients with olp in an iranian population. materials and methods. thirty-two patients with olp and 32 age-matched healthy volunteers as a control group were included in this study. serum tests ...

background and aims. lichen planus is a relatively common mucocutaneous disease, with an unknown etiology. there is no complete cure for oral lichen planus (olp), but some drugs, including corticosteroids, retinoids, cyclosporine and antibiotics are commonly used for treatment of olp. the aim of the present study was to compare the effect of combination of triamcinolone and vitamin a mouthwash ...

unstimulated whole salivary p53 was evaluated in non-involved subjects, in patients suffering from oral lichen planus (olp) and squamous cell carcinoma (scc). a total of 34 patients with olp, 24 patients suffering from oral scc and 41 non-involved participants were enrolled. the unstimulated whole saliva p53 level was assayed by elisa. data was analyzed by anova followed by the tukey post hoc t...

background: the association between oral lichen planus (olp) as a common oral disease and hcv infection as an etiological factor in the development of hepatocellular carcinoma has been widely reported. however, there are wide geographical variations in the reported prevalence. this study was performed to determine the prevalence of l. planus in hcv+ patients in shiraz, southern iran. â  methods...

background oral lichen planus (olp) is a chronic inflammatory disease affecting the oral mucosa in 0.5-2% of the world’s population. it is more common in women compared to men and the mean age at the onset of the lesion is the fourth decade. objectives the purpose of this study was to evaluate the presence of helicobacter pylori (h. pylori) in oral lichen planus and oral lichenoid reaction. mat...

background: oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. the role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. vascular endothelial growth factor (vegf) is an important regulator of angiogenesis. we aimed to evaluate the serum level of vegf in patients with oral lichen planus compared with normal in...

Oral lichen planus is a common multifactorial disease. This article is not a complete review of the disease, but instead a discussion of selected aspects such as clinical features, possible vascular influences, and the relation of stress and drugs and metals to the disease. Immunologic theories and cancerous potentials are discussed critically. Finally, a detailed treatment plan of the inflamma...

Oral lichen planus is a chronic inflammatory immune-mediated disease. ICAM-1 and VCAM-1 are vascular adhesion molecules that their receptors are located on endothelial cells and leukocytes. The aim of this study is the immunohistochemical evaluation of VCAM1 and ICAM1 in oral lichen planus and to compare these two markers with normal mucosa for evaluation of angiogenesis. This descriptive-analy...

BACKGROUND Oral lichen planus (OLP) is a common chronic inflammatory mucocutaneous disease. Clinical diagnosis of OLP requires clinical work-up and histologic examination to rule out possible dysplasia and carcinoma. It is possible that oral mucosal viral infections including HPV infection may have a causative role in OLP pathogenesis. The aim of this study was to examine the coincidence of hum...