Received for publication 26 October 1976 and in revised form 24 January 1977. INTRODUCTION The fat cell adenylate cyclase is a plasma membrane-bound enzyme which is supposed to play a central role in the stimulation of lipolysis by hormones (1). The rat fat cell enzyme reacts to a variety of hormones including catecholamines and peptide hormones such as ACTH, glucagon, and secretin (2-4). By co...

1. The effect of parathyroid hormone on gastric bicarbonate secretion was determined in the anaesthetized guinea pig. Subcutaneous injections of bovine parathyroid hormone (75 U.S.P units day-1 kg-1) for 7 days caused a significant increase in HCO3- output. There was also a rise in K+ output and a slight elevation of H+ secretion. A similar increase in HCO3- output occurred after acute intraven...

Novel surgical applications include radioguided procedures in parathyroidectomy operations. In order to investigate the feasibility of usage of the portable gamma camera in parathyroidectomy operations; intraoperative radioguided parathyroidectomy operation was performed in three hyperparathyroidism patients with inconclusive preoperative parathyroid scintigraphy results. Intraoperative portabl...

A 4-year-old girl presented with progressive distension of the abdomen and bowing of the legs (genu valgum) since birth. She was anemic, with a blood pressure of 180/110 mmHg. The serum level of creatinine was 1.7 mg/dL. She had hypocalcemia, and elevated serum level of phosphorous and parathyroid hormones. Ultrasonography revealed bilateral grossly hydronephrotic kidneys with thinned out paren...

Non-traditional risk factors substantially contribute to cardiovascular (CV) disease. A deranged calcium-phosphate metabolism-first identified as a major non-traditional CV risk factor in patients with chronic kidney disease-may be implicated in development and progression of CV disease even among individuals with intact renal function. This review thus summarizes epidemiological and experiment...

ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. this study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. from march 2008 to march 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 mhz) of the parathyroid glands in compari...

INTRODUCTION Chronic renal failure is associated with endocrine abnormalities, which in some cases cause polyendocrinopathy responsible for the symptoms and complications. The consequence of secondary hyperparathyroidism is not only bone disease but may be cardiovascular disorders, peripheral nerve damage and impact on the level of sex hormones. THE AIM To evaluate the interactions between pa...

Abstract Funding Acknowledgements Type of funding sources: None. Aim To investigate the role markers vascular inflammation, vitamin D, parathyroid hormone as predictors increased pulse-wave velocity (PWV) and degenerative bone changes in postmenopausal women with arterial hypertension (AH). Methods 164 females were examined. Gr.1 included 42 healthy individuals, Gr.2 - 58 patients AH Gr.3 64 os...

Stanniocalcin 1 and stanniocalcin 2 are two glycoprotein hormones, which act as calcium phosphate-regulating factor on intestine and kidney. We have previously reported that stanniocalcin 2 expression is positively and negatively controlled by 1,25(OH)(2)D(3) and parathyroid hormone in renal proximal tubular cells. However, it has been unclear whether they regulate the stanniocalcin 1 gene expr...

AbstractParathyroid adenoma is a benign tumor of the parathyroid glands. The cause of most parathyroid adenomas is unknown. Parathyroid adenoma increases the secretion of parathyroid hormone and results in primary hyperparathyroidism. High amounts of parathyroid hormone in the blood cause the imbalance of calcium, which leads to various complications such as kidney stones, depression, lethargy,...