RESULTS: Fifty-five participants (31 patients and 24 parents) completed all questionnaires, 98.2% preferred active involvement in therapeutic decision-making. The SDM-Q-9 scores, assessed by patients and physicians, were acceptable (mean 68 out of 100). However, the independently assessed OPTION-5 scores were significantly lower (mean 31 out of 100). In the consultations, physicians rarely aske...

The demand and growth for published research in the field of multiple sclerosis (MS) has increased exponentially over the last few years. The primary aim of the Multiple Sclerosis Journal (MSJ) has always been to reflect the excellent work of the ever-expanding and diverse clinical and research field of MS, and this role will now be shared by MSJ’s companion journal MSJ Experimental, Translatio...

In this article we present an approach for tackling three important aspects of text normalization: sentence boundary disambiguation, disambiguation of capitalized words in positions where capitalization is expected, and identification of abbreviations. As opposed to the two dominant techniques of computing statistics or writing specialized grammars, our document-centered approach works by consi...

The immune microenvironment is considered a major obstacle to generating an effective antitumor immune response. Checkpoint inhibitors manipulate the co-stimulatory response between antigen-presenting cells and immune cells-or between the tumor and immune cells-to elicit an antitumor immune response that would have otherwise been suppressed. Checkpoint inhibitors have shown great promise in the...

BACKGROUND AND CONTEXT Many countries are giving patients a more active role in health care, on both the individual and collective level. This study focuses on one aspect of the participation agenda on the individual level: self-management. The study explores self-management in practice, including the implications of the difficulties encountered. OBJECTIVE To gain insight into the complexity ...