McCune-Albright syndrome (MAS) is characterized by a triad of poly/monostotic fibrous dysplasia, café-au-lait macules and hyperfunctioning endocrinopathies including human growth hormone excess. Acromegaly as a manifestation of endocrine hyperfunction with MAS is uncommon. Surgical excision may be challenging due to the associated severe fibrous dysplasia of the skull base. Through the endoscop...

A 24-year old female patient with the history of pressure ulcers in distal extremities resulted in severe deformity will be reported. Her disease started when she was 9 years old and a similar history was found in her brother. In physical examination, pain and temperature sensations were impaired in distal extremities. Nerve conduction velocity showed impaired sensory and normal motor responses...

background: diabetic peripheral neuropathy (dpn) accounts for 80% of diabetic foot ulceration; therefore neurologic examination plays a critical role in screening at risk patients. our objective was assessment the prevalence of dpn and related factors based on clinical findings. methods: this cross-sectional study was conducted on 124 diabetics who were randomly recruited from diabetes clinic o...

Outcome measurements are essential to monitor the clinical course or treatment response of peripheral neuropathy. Even though there no designated standard scale for neuropathy currently, several scales were validated use outcome based on many researches. Here, we reviewed commonly used and fulfilled clinimetric properties in neuropathy, especially focusing inflammatory (Guillain-Barré syndrome,...

Leprosy is a major cause of peripheral neuropathy in developing countries, affecting sensory, motor, and autonomic nerve function. Neuropathy complications can include sensory loss muscle weakness. Impaired function often the first symptom encountered leprosy neuropathy. Early detection treatment are important to prevent disability.