Although semen is the principal vector of human immunodeficiency virus (HIV) dissemination worldwide, the origin of the infected leukocytes and free viral particles in this body fluid remain elusive. Here we review the accumulated evidence of the genital origin of HIV in semen from therapy naive individuals and men receiving suppressive highly active antiretroviral therapy (HAART), summarize th...

The subresultants play a fundamental role in elimination theory and computer algebra. Recently they have been extended to Ore polynomials. They are de ̄ned by an expression in the coe±cients of Ore polynomials. In this paper, we provide another expression for them. This expression is written in terms of the \solutions" of Ore polynomials (in \generic" case). It is a generalization of our previou...

PURPOSE Diffusion MRI has recently been used with detailed models to probe tissue microstructure. Much of this work has been performed ex vivo with powerful scanner hardware, to gain sensitivity to parameters such as axon radius. By contrast, performing microstructure imaging on clinical scanners is extremely challenging. METHODS We use an optimized dual spin-echo diffusion protocol, and a Ba...

the main objective of this paper is to examine the impact of economic growth on coefficient of cardinal welfare in iran’s economy. hence, we employ the bayesian approach and the estimation of forward and backward density functions in order to measure the effect of economic growth spillovers on the social welfare. the paper has applied the gibbs sampling algorithm which is a rigorous tool for fo...

OBJECTIVES: To compare the estimated first-line treatment costs of extended-release tolterodine versus controlled-release oxybutynin in patients with overactive bladder patients (OAB). METHODS: Data from a randomized clinical trial (Curr Med Res Opin 2002; 18:177–184), showing greater improvement in bladder condition for patients taking extended-release tolterodine compared to controlled-releas...

BACKGROUND Achievement of durable responses in patients with relapsed/refractory peripheral T cell lymphoma (PTCL) is challenging with current therapies, and there are few data regarding the potential benefits of continuing treatment in patients with the best response of stable disease (SD). Histone deacetylase inhibitors are a novel class of drugs with activity in T cell malignancies. Romideps...

Immune-modulatory drugs are active in immunoglobulin light-chain amyloidosis and the addition of alkylating agents can potentiate their action. In this phase II prospective trial we used cyclophosphamide, lenalidomide and dexamethasone in the treatment of 21 patients who were refractory (n=13, 62%) or relapsed (n=8, 38%) after prior treatment including melphalan in all cases, bortezomib in 4 an...

This is a retrospective study to evaluate the prevention of complications of metallic stent placement in patients with unresectable advanced esophageal cancer. A total of 87 patients were treated with 4 types of metal stents in the esophagus over a period of 18 years. Stent placement was technically successful. The most common prior treatment was chemoradiotherapy. There were no significant dif...

The clinical response and survival of 113 patients with at least 3-year follow-up after treatment with fludarabine as a single agent for chronic lymphocytic leukemia has been evaluated. Seventy-eight patients were previously treated and 35 were untreated. The response to therapy and survival were strongly correlated with the degree of previous therapy, the stage of disease, and whether or not t...