objective(s):multi-epitopic protein vaccines and direction of vaccine delivery to dendritic cells (dcs) are promising approaches for enhancing immune responses against mutable pathogens. escherichia coli is current host for expression of recombinant proteins, and it is important to optimize expression condition. the aim of this study was the optimization of multi-epitopic hiv-1 tat/pol/gag/env ...

abstract this study is an attempt to investigate the influence of targeting subsidies on price transmission pattern in iran's egg market. the targeting subsidies plan was imposed by 20 december 2010. using of daily price time series data, the study was conducted during december 2009 to october 2011. using ecm model, price transmission models were estimated for the two periods (e.g. before and a...

temperature restrictions on aqueous effluents dictate that streams with a temperature higher than the permitted level needed to pass through cooling systems to reduce the effluent temperature before discharge. in this study, by considering the grouping design rules based on pinch technology, an optimum design for a distributed effluent cooling system, has been developed. a counter-flow wet cool...

avicenna (980 – 1037 ad) known as the prince of physicians in the west was one of the most prominent persian thinkers, philosophers, and physicians. owing to his interests in cardiology, he authored considerable works on different aspects of cardiology. “resaley-e-ragshenasi” (book on pulsology) and”kitab al-adviyt- ol-qalbiye” (the book on drugs for cardiovascular diseases) are avicenna’s grea...

This paper describes the application of process integration principles to the design of oil refineries hydrogen network. In this regard, a design hierarchy as well as heuristics and required guidelines are proposed. The recommended rules compensate lack of procedure to the design and make the design process easier. The guiding principles of the design are based upon pinch technology and ext...

the purpose of this study, determining the optimal cultivation pattern by using interval mathematical programming approach among the farmers of esfarayen county before and after targeting the subsidies. for this purpose, farmers based on water resources classified in three group of using the river water, deep wells water and rainfed cultivation. the required data for this study has been obtaine...

among the drug delivery and targeting (ddt) routes, lung alveolar epithelium has been given enormous attentions in terms of the delivery of a wide range of macromolecules such as gene- or protein-based nanopharmaceuticals. however, little is known about cellular modulation of lung transport characteristics by endogenous and/or exogenous agents. thus, in the current study, impact of dexamethason...