Sir, The anti-convulsant drug carbamazepine may induce generalized exanthema or, less frequently, severe cutaneous eruptions, such as hypersensitivity syndrome or toxic epidermal necrolysis. The development of psoriasiform eruptions and the exacerbation of pre-existing psoriasis have been recognized as common adverse reactions to beta-blockers, lithium and antimalarials (1). Additional causativ...

Sex hormone allergy as a clinical syndrome has been known for almost a century. Due to the diversity of clinical presentation regarding symptoms and disease patterns, the optimal patient care represents an enormous interdisciplinary challenge. Frequently, hypersensitivity reactions affect more than one sex hormone and double positive tests for estrogen and progesterone have been described. Sinc...

As pleiotropic coregulators, members of the p160/steroid receptor coactivator (SRC) family control a broad spectrum of transcriptional responses that underpin a diverse array of physiological and pathophysiological processes. Because of their potent coregulator properties, strict controls on SRC expression levels are required to maintain normal tissue functionality. Accordingly, an unwarranted ...

Introduction: Nowadays, several casein components such as casein phosphopeptide amorphous calcium phosphate (CPP-ACP) are vastly considered as a suitable replacement for fluoride component . The aim of this study was to compare the effect of CPP-ACP paste and fluoride varnish on dentin hypersensitivity reduction. Materials & Methods: In this clinical trial study, thirty adult patients betwee...

at present the only available management for food allergy is avoidance; however, abstaining from allergic foods can affect the quality of life. oral immunotherapy (oit) is an efficient method for increasing tolerance towards food allergens. the aim of this study was desensitizing patients above five years of age with wheat allergy and evaluating the safety and efficacy of oit for children with ...

allergic asthma is the most common acute inflammatory airway disorder and their incidence population has exploded in the last years, being estimated that over 300 million people worldwide have the condition. here, we present a brief overview of relationship of allergic asthma with diet and food intake. several studies have shown that most asthma cases are due to an allergic immune response to e...

The antitumor agent cisplatin and progesterone separate joint action on content of total phospholipids their individual fractions in nuclei from rat thymus cells were investigated. When used separately, exhibit its own distinctive properties. Cisplatin reduces, progesterone, the contrary, increases phospholipids. together, effects these drugs are summed up. Thus phospholipid cell by 17% after i...

orthodontic treatment of individuals with metal hypersensitivity is a matter of concern for the orthodontist. orthodontic appliances contain metals like nickel, cobalt and chromium etc. metals may cause allergic reactions and are known as allergens. reaction to these metals is due to biodegradation of metals in the oral cavity. this may lead to the formation of corrosion products and their expo...

the aim of this study was to evaluate changes that occur in motility parameters of progesterone treated mouse spermatozoa during course of hyperactivation. mouse spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min of incubation. for each sperm, one second of movement of the head-midpiece junction was traced from the videotape and for each tracing sev...

discussion early recognition of dress syndrome is of a particular importance. although rare, in newborn infants with the presence of skin rash, liver involvement, hyper-eosinophilia and lymphadenopathy, dress diagnosis should be highly suspected and prompt intervention including withdrawal of causative drug is required to prevent potentially fatal outcomes. introduction drug rash with eosinophi...