progesterone hypersensitivity (ph) is a rare clinical condition that  displays hypersensitivity to  endogenous  or  exogenous progesterone.  it  is characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses. we present  a  case of  24-year-old woman  showing severe angioedema attacks occurring from the first day of her menstruation a...

Progesterone hypersensitivity (PH) is a rare clinical condition that displays hypersensitivity to endogenous or exogenous progesterone. It is characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses. We present a case of 24-year-old woman showing severe angioedema attacks occurring from the first day of her menstruation and continu...

Hypersensitivity to progesterone is a rare condition, and it represents a hypersensitivity reaction to endogenous progesterone. Here we report a case of a woman who presented to our attention for evaluation of a rash for a few years on her posterior elbows, forearms, and right lateral lower extremity. We report this case because it describes a rare clinical entity, with an atypical clinical pre...

BACKGROUND Progesterone is emerging as an important protective agent against various injuries to the nervous system. Neuroprotective and remyelinating effects have been documented for this neurosteroid, which is synthesized by, and acts on, the central and peripheral nervous systems. Neuropathic pain is a severe, persistent condition that is generally resistant to treatment, and poses major per...

APD: autoimmune progesterone dermatitis EM: erythema multiforme HSV: herpes simplex virus IDP: intradermal progesterone TAH-BSO: total abdominal hysterectomyebilateral salpingo-oophorectomy INTRODUCTION HIV infection is a known risk factor for a host of mucocutaneous conditions, most notably drug hypersensitivity reactions. We describe an unusual case of mucosal autoimmune progesterone dermatit...

We report two cases of acute eosinophilic pneumonia induced by i.m. administration of progesterone used as luteal phase support after IVF. For both patients, the symptoms began 3 weeks after the first injection of progesterone. Both patients were in respiratory distress, and one of them required ventilatory assistance for a week, with 5 days in the intensive care unit. Symptoms improved as the ...