background: controlled ovarian stimulation combined with intra uterine insemination (iui) is a convenient treatment of infertility with a success rate of 11%. the clinical observation and pattern of progesterone secretion in this method is suggestive of luteal phase defect and postulated as an implicating factor of treatment failure. objective: to investigate the efficacy of luteal phase suppor...

Background: The role of estrogen and progesterone in stroke is suggested in previous studies, but yet is controversial. Objectives: Comparing the plasma levels of estrogen and progesterone and their ratio in ischemic stroke patients and healthy population. Materials and Methods: This cross-sectional comparative study was conducted from March to September of 2013. Sixty-six female patients older...

introduction: following a traumatic brain injury (tbi), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. this study examined the changes in brain concentrations of proinflammatory cytokines il-1, il-6, tnf-α and tgf- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post-in...

Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post...

Progesterone withdrawal is essential for parturition, but the mechanism of this pivotal hormonal change is unclear in women and other mammals that give birth without a pre-labor drop in maternal progesterone levels. One possibility suggested by uterine tissue analyses and cell culture models is that progesterone receptor levels change at term decreasing the progesterone responsiveness of the my...

OBJECTIVE To evaluate the predictive value of the progesterone level at the beta-human chorionic gonadotropin (β-hCG) check day for ongoing pregnancy maintenance in in vitro fertilization (IVF) cycles in women with previous unexplained repeated miscarriages. MATERIALS AND METHODS One hundred and forty-eight women, with visible gestational sac after IVF, were recruited in this observational st...

INTRODUCTION Progesterone-treated females eat more food, but the mechanism underlying this effect is not well understood. The aim of the study was to analyse the effect of progesterone on neuropeptide genes expression in rat hypothalamus. MATERIAL AND METHODS Experiments were carried out on female and male Wistar rats. Animals were treated with progesterone (100 mg per rat) for 28 days. NPY a...

Abstract Background This study aimed at determining the predictive value of human chorionic gonadotropin and progesterone levels on pregnancy outcomes in patients receiving vitro fertilization due to fallopian tube associated infertility. Methods We retrospectively analyzed clinical data 854 cycles infertility fresh embryo transfer. The had been collected from January 2010 December 2018 was div...

Effects of hypophysectomy or reduction of the conceptus number on luteal steroidogenesis were studied in the pregnant rat. On day 7 of pregnancy (day 1 = day of insemination), the number of conceptuses was adjusted to one by aspirating all but one conceptus from the uterus. Another group of rats received hypophysectomy on day 12 of pregnancy. On day 15 of pregnancy, the weights of the corpora l...