The determinants of selective vulnerability in neurodegenerative diseases remain elusive. The asymmetric loss of neurons in primary progressive aphasia offers a unique setting for addressing this question. Although no factor can yet account for the selective vulnerability of the left hemisphere language network to degenerative diseases, a few themes are emerging as potential targets of further ...

in islamic mysticism by annihilation it is meant the removal of any determination, tendency of delimitation to non-delimitation and transformation of multiplicity into unity. the study of historical development of the concept of annihilation can be helpful in understanding and analyzing this fundamental doctrine of mysticism. in early mystical works extant in world of islam, hardly can one find...

OBJECTIVE To investigate the natural history and prognostic factors in patients with nonhereditary, adult-onset progressive muscular atrophy. DESIGN Inception cohort conducted for 18 months. Settings Three university hospitals in the Netherlands (referral centers for neuromuscular diseases). Patients Thirty-seven consecutive patients newly diagnosed (onset of weakness <4 years) with progressi...

background: patients with b-cell chronic lymphocytic leukemia (b-cll) have hetero-geneous clinical courses, thus several biological parameters need to be added to the cur-rent clinical staging systems to predict disease outcome. recent immunophenotypic stud-ies performed mainly in western populations have demonstrated the prognostic value of cd38 and zap-70 expression in b-cll. objectives: to i...

multiple sclerosis is an autoimmune disease caused by damage to the myelin of the nerve cells in the spinal cord and brain, ms was classified into 4 types including: relasping/remitting (rr) primary/progressive (pp), secondary/progressive (sp), progressive/relapsing (pr). pr ms is one of the severe forms of ms that lead to inflammation associated physical, mental and vision dysfunction. because...

desertification of the arid and semi-arid lands of the world has been proceeding for more than a thousand years.human-induced degradation in these areas is regularly cited as one of the principal causes of desertification.euphrates and tigris basin as the case study of this research in some aspects is almost unique in the world. but thisbasin has been confronted to progressive desertification. ...