The Proton Therapy Center in Orsay (CPO) and CEA/DAPNIA launched the joint project on Monte Carlo modeling of a CPO beam line with the aim to achieve a prediction of dose distribution in all the calibration configurations (depth and the shape of the tumor) better than 2%. The calculation module is intended to be used for the absolute dosimetry of the clinical beam (patient Quality Assurance – Q...

Introduction: Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed. Three alpha particles with an average energy around 4MeV are emitted from the point of reaction between a proton and boron. In addition, the 719 keV prompt gamma emitted by the proton Boron fusion reactions can be used for on-...

Introduction Proton therapy is used to treat malignant tumors such as melanoma inside the eye. Proton particles are adjusted according to various parameters such as tumor size and position and patient’s distance from the proton source. The purpose of this study was to assess absorbed doses in eyes and various tumors found in the area of sclera and choroid and the adjacent tissues in radiotherap...

Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

Introduction: One crucial point when calculating the distribution of doses with ions is the uncertainty of the Bragg peak. The proton ranges in determined geometries like homogeneous phantoms and detector geometries can be calculated with a number of various parameterization models. Several different parameterizations of the range-energy relationship exist, with different level...

introduction today, there is a growing interest in the use of hadrontherapy as an advanced radiotherapy technique. hadrontherapy is considered a promising tool for cancer treatment, given its high radiobiological effectiveness and high accuracy of dose deposition due to the physical properties of hadrons. however, new radiation modalities of dose delivery and on-line beam monitoring play crucia...

Abstract Purpose: Advanced radiation therapy techniques use small fields in treatment planning and delivery. Small have the advantage of more accurate dose delivery, but with cost some complications dosimetry. Different calculation algorithms imported various systems (TPSs) which each them has different accuracy. Monte Carlo (MC) simulation been reported as one methods for calculating distribut...

background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background: in radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. metho...