objective(s): the present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. materials and methods: forty eight wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. animals were placed in a hypoxia chamber and instrumented with epidural catheters at the th...

Background: Children with congenital heart disease (CHD) are prone to malnutrition and growth retardation. This study aimed to compare growth status between children with CHD and healthy children.                Materials and Methods: This case–control study included 310 children with CHD and 300 healthy children matched in age and gender. CHD patients grouped according to cardiac diagnosis: ...

Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D d...

now-a-days truncus arteriosus has been known as “common arterial trunk” (cat) and is an uncommon congenital cardiac defect presenting in about 1-3% congenital heart disease. environmental and genetic factors effects on incidence of cat and other conotruncal anomalies. the majority patients with cat and 22q11 deletion have other anomalies such as hypoplasia or aplasia of the thymus or parath...

conclusions increasing evidence supports the use of ecmo as a bridge to lt, reporting good outcomes. in the modern era of pah therapy, it is feasible to use prolonged ecmo support as a bridge to lung transplant, with the aim of weaning off this support; however, its use requires more experience and knowledge of long-term outcomes. introduction the use of extracorporeal membrane oxygenation (ecm...

conclusions based on the results of this study, we suggest the use of a novel “time from the beginning of isovolumetric contraction to the peak of the s wave” (ttp) parameter in the tdi of the base of the rv free wall to predict ph with acceptable accuracy in comparison with rhc. results in our study, the ttp showed a significant inverse relationship with the pap. based on our results, a ttp of...

cor triatriatum is an acyanotic congenital heart disease. we present a rare case of cor triatriatum sinistrum in a 6-month-old female infant who was presented with cyanosis and failure to thrive. the 2d transthoracic echocardiography and the doppler color flow imaging showed a proximal venous chamber communicating to the distal left atrium  through restrictive opening to the low-pressure, dista...