Background: Intra-operative radiation therapy (IORT) is the transfer of a single large radiation dose to the tumor bed during surgery with the final goal of improving regional tumor control. This study aimed to investigate the safety, effectiveness and economic evaluation of intra-operative radiation therapy.   Methods : The scientific literature was searched in the main biomedical databases ...

introduction:   palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. the most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local puva. frequently, it is a recalcitrant disease. we investigated the efficacy and tolerability of the combination of topical calcipot...

background: the assessment of rbe quantity in the treatment of cancer tumors with proton beams in treatment planning systems (tps) is of high significance. given the significance of the issue and the studies conducted in the literature, this quantity is fixed and is taken as equal to 1.1. objective: the main objective of this study was to assess rbe quantity of proton beams and their variations...

objective(s): radiation therapy for breast cancer can induce myocardial capillary injury and increase cardiovascular morbidity and mortality. a prospective cohort was conducted to study the prevalence of myocardial perfusion abnormalities following radiation therapy of left-sided breast cancer patients as compared to those with right–sided cancer. methods: to minimize potential confounding fact...

Background: Radiation therapy is among the most conventional cancer therapeutic modalities with effective local tumor control. However, due to the development of radio-resistance, tumor recurrence and metastasis often occur following radiation therapy. In recent years, combination of radiotherapy and gene therapy has been suggested to overcome this problem. The aim of the current study was to e...

an important need in radiation therapy is a fast and accurate treatment planning system. this system using ct data and characteristics of the radiation beam, calculates the dose in all points of the patient’s volume. two main factors in planning system are “accuracy” and “speed”. according to these factors, various generation of treatment planning systems are developed.   this article is the re...