Mohamad Amin Mosleh-Shirazi
Shiraz University of Medical Sciences, Shiraz, Fars,
[ 1 ] - FLUENCE MAP OPTIMIZATION IN INTENSITY MODULATED RADIATION THERAPY FOR FUZZY TARGET DOSE
Although many methods exist for intensity modulated radiotherapy (IMRT) fluence map optimization for crisp data, based on clinical practice, some of the involved parameters are fuzzy. In this paper, the best fluence maps for an IMRT procedure were identifed as a solution of an optimization problem with a quadratic objective function, where the prescribed target dose vector was fuzzy. First, a d...
[ 2 ] - The influence of using different reconstruction algorithms on sensitivity of quantitative 18F-FDG-PET volumetric measures to background activity variation
Introduction: This study aims to investigate the influence of background activity variation on image quantification in differently reconstructed PET/CT images. Methods: Measurements were performed on a Discovery-690 PET/CT scanner using a custom-built NEMA-like phantom. A background activity level of 5.3 and 2.6 kBq/ml 18F-FDG were applied. Ima...
[ 3 ] - Radiotherapy techniques for intracranial tumours
ABSTRACTIntracranial tumours often require radiotherapeutic approaches that differ from other sites. Their specific requirements merit a specialized discussion. A brief review of radiotherapy techniques to treat intracranial tumours is presented with emphasis on the author’s own experience and work, where appropriate. A clinical introduction is presented first followed by a description of bot...
[ 4 ] - Measurement of the immobilisation efficacy of a head fixation system
Background: In order to assign appropriate planning target volume (PTV) margins, each centre should measure the patient positioning deviations for their set-up techniques. At the Royal Marsden Hospital, UK, a conformal shell (cast) system is used when a stereotactic frame is not suitable. In this paper, we report on a series of measurements with the aim of obtaining the systematic and random ...
[ 5 ] - Synergistic Effects of NDRG2 Overexpression and Radiotherapy on Cell Death of Human Prostate LNCaP Cells
Background: Radiation therapy is among the most conventional cancer therapeutic modalities with effective local tumor control. However, due to the development of radio-resistance, tumor recurrence and metastasis often occur following radiation therapy. In recent years, combination of radiotherapy and gene therapy has been suggested to overcome this problem. The aim of the current study was to e...
[ 6 ] - Assessment of Adaptive Response of Gamma Radiation in the Operating Room Personnel Exposed to Anesthetic Gases by Measuring the Relative Gene Expression Changes Ku80, Ligase1 and P53
Background: Some operating room personnel are occupationally exposed to genotoxic agents such as anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA (priming dose), which in the subsequent exposure to higher dose of those factors (challenging dose), show more resistance and sensibility.. <b...
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