The rostroventromedial medulla (RVM), together with the periaqueductal gray matter (PAG), constitutes the descendent antinociceptive system. Additionally, these structures mutually regulate defensive behaviors, including tonic immobility (TI) in guinea pigs. The current study was undertaken to evaluate the connections of the RVM with the PAG and the spinal cord in guinea pigs in order to provid...

Objective(s): There are many reports about the role of rostral ventromedial medulla (RVM) in modulating stress-induced analgesia (SIA). In the previous study we demonstrated that temporal inactivation of RVM by lidocaine potentiated stress-induced analgesia. In this study, we investigated the effect of permanent lesion of the RVM on SIA by using formalin test as a model of acute inflammatory pa...

The optimization of kernel parameters is an important step in the application of the Relevance Vector Machine (RVM) for many real-world problems. In this paper, firstly we have developed an improved anisotropic Gaussian kernel as the kernel function of the RVM model, whose parameters are optimized by Bacterial Foraging Optimization (BFO). Then the proposed method is applied to describing the pr...

The present study involves a novel computational technique, regarding simultaneous use of the pseudo particle method, Poisson integral method and a special-purpose computer originally designed for molecular dynamics simulations (MDGRAPE-3). In the present calculations, the dynamics of two colliding vortex rings have been studied using the vortex method. The present acceleration technique allows...

Random vortex methods are applied to the analysis of boundary layer instability in two and three space dimensions. A thorough discussion of boundary conditions is given. In two dimensions, the results are in good agreement with known facts. In three dimensions, a new version of the method is introduced, in which the computational elements are vortex segments. The numerical results afford new in...