Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

objective: to study the mechanisms involved in amyloid formation processes, we made a mammalian cell culture model of amylin aggregation and characterized its properties. materials and methods: amyloid fibrils were extracted from cho cells and binding affinity to thioflavin t and congo red was investigated. then the apple-green birefringence of extracted fibrils was detected under polarized li...

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

Hypoxia, which commonly associates with respiratory and cardiovascular diseases, provokes an acute inflammatory response. However, underlying mechanisms are not well understood. Here we report that red blood cells (RBCs) induce hypoxic inflammation by producing reactive oxygen species (ROS) that diffuse to endothelial cells of adjoining blood vessels. Real-time fluorescence imaging of rat and m...

background: it is not clear whether the use of volumetric peristaltic infusion pumps, affect the quality of the erythrocytes during packed cell transfusion or not. in the present study in vitro quality of red blood cells was assessed after using this type of infusion pumps in a prospective study. materials and methods: in this study 60 units of packed red cells were examined before and after pa...

results sickle cells were observed among 20% of subjects with the dilution of 1:50 and 70% of subjects with the dilution of 1:100. mean percentage of sickle red cells with dilutions of 1:50, 1:100 and 1:200 were 3.75%, 25.75% and 43.0%, respectively. conclusions it is suggested that c. fistula may protect rbc against sickling, in hypoxic conditions, in individuals with hbs gene defect. objectiv...

objective: the exfoliated human deciduous tooth (shed) contain multipotent stem cells that identified to be a population of highly proliferative and clonogenic .these cells are capable of differentiating into a variety of cell types including neural cells, adipocytes, and odontoblasts. material and methods: normal exfoliated human deciduous incisors collected from six- to nine-years-old childre...